Nafronyl Oxalate may be available in the countries listed below.
Nafronyl Oxalate (USAN) is also known as Naftidrofuryl (Rec.INN)
International Drug Name Search
Glossary
| Rec.INN | Recommended International Nonproprietary Name (World Health Organization) |
| USAN | United States Adopted Name |
Metronidazol L.CH. may be available in the countries listed below.
Metronidazole is reported as an ingredient of Metronidazol L.CH. in the following countries:
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Nordurine may be available in the countries listed below.
Desmopressin acetate (a derivative of Desmopressin) is reported as an ingredient of Nordurine in the following countries:
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Flokisyl may be available in the countries listed below.
Ciprofloxacin is reported as an ingredient of Flokisyl in the following countries:
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Losacor may be available in the countries listed below.
Losartan potassium salt (a derivative of Losartan) is reported as an ingredient of Losacor in the following countries:
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Nafti-Sandoz may be available in the countries listed below.
Naftidrofuryl oxalate (a derivative of Naftidrofuryl) is reported as an ingredient of Nafti-Sandoz in the following countries:
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Virucid may be available in the countries listed below.
Aciclovir is reported as an ingredient of Virucid in the following countries:
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Prexanil Combi may be available in the countries listed below.
Indapamide is reported as an ingredient of Prexanil Combi in the following countries:
Perindopril is reported as an ingredient of Prexanil Combi in the following countries:
Perindopril erbumine (a derivative of Perindopril) is reported as an ingredient of Prexanil Combi in the following countries:
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Kin Crema may be available in the countries listed below.
Ibuprofen is reported as an ingredient of Kin Crema in the following countries:
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In some countries, this medicine may only be approved for veterinary use.
Neomycin sulfate (a derivative of Neomycin) is reported as an ingredient of Biosol in the following countries:
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Paroxetin-Teva may be available in the countries listed below.
Paroxetine hydrochloride (a derivative of Paroxetine) is reported as an ingredient of Paroxetin-Teva in the following countries:
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Acetilcisteina Sandoz may be available in the countries listed below.
Acetylcysteine is reported as an ingredient of Acetilcisteina Sandoz in the following countries:
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Gentamicin-mp may be available in the countries listed below.
Gentamicin sulfate (a derivative of Gentamicin) is reported as an ingredient of Gentamicin-mp in the following countries:
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Ciprofloxacine Arrow may be available in the countries listed below.
Ciprofloxacin hydrochloride (a derivative of Ciprofloxacin) is reported as an ingredient of Ciprofloxacine Arrow in the following countries:
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Meto-Tablinen may be available in the countries listed below.
Metoprolol tartrate (a derivative of Metoprolol) is reported as an ingredient of Meto-Tablinen in the following countries:
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Emconcor CHF may be available in the countries listed below.
Bisoprolol fumarate (a derivative of Bisoprolol) is reported as an ingredient of Emconcor CHF in the following countries:
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Profertil may be available in the countries listed below.
Clomifene citrate (a derivative of Clomifene) is reported as an ingredient of Profertil in the following countries:
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Malaria Med may be available in the countries listed below.
Pyrimethamine is reported as an ingredient of Malaria Med in the following countries:
Sulfadoxine is reported as an ingredient of Malaria Med in the following countries:
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Phenazolinum may be available in the countries listed below.
Antazoline is reported as an ingredient of Phenazolinum in the following countries:
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Taricin may be available in the countries listed below.
Ofloxacin is reported as an ingredient of Taricin in the following countries:
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Rx only
For External Use Only. Not for Ophthalmic Use.
Betamethasone Valerate Cream USP, 0.1% contains a topical corticosteroid, Betamethasone Valerate. The topical corticosteroids constitute a class of primarily synthetic steroids used as anti-inflammatory and antipruritic agents.
Betamethasone Valerate is chemically designated as Pregna-1, 4-diene-3, 20-dione, 9-fluoro-11, 21-dihydroxy-16-methyl-17 [(1-oxopentyl) oxy], (11β, 16β)-.
MF: C27H37FO6
MW: 476.58
Each gram of Betamethasone Valerate Cream USP, 0.1% contains: 1.2 mg Betamethasone Valerate (equivalent to 1.0 mg betamethasone), in an aqueous vanishing cream base of mineral oil, white petrolatum, polyethylene glycol 1000, ceteareth-15, cetyl alcohol, stearyl alcohol, propylene glycol, purified water, and 4-chloro-m-cresol as preservative.
Betamethasone Valerate cream as a topical corticosteroid has anti-inflammatory, antipruritic and vasoconstrictive actions.
The mechanism of anti-inflammatory activity of the topical corticosteroids is unclear. Various laboratory methods, including vasoconstrictor assays, are used to compare and predict potencies and/or clinical efficacies of the topical corticosteroids. There is some evidence to suggest that a recognizable correlation exists between vasoconstrictor potency and therapeutic efficacy in man.
The extent of percutaneous absorption of topical corticosteroids is determined by many factors including the vehicle, the integrity of the epidermal barrier, and the use of occlusive dressings.
Betamethasone Valerate cream can be absorbed from normal intact skin. Inflammation and/or other disease processes in the skin increase percutaneous absorption. Occlusive dressings substantially increase the percutaneous absorption of topical corticosteroids. Thus, occlusive dressings may be a valuable therapeutic adjunct for treatment of resistant dermatoses (see DOSAGE AND ADMINISTRATION).
Once absorbed through the skin, Betamethasone Valerate cream is handled through pharmacokinetic pathways similar to systemically administered corticosteroids. Corticosteroids are bound to plasma proteins in varying degrees. They are metabolized primarily in the liver and are then excreted by the kidneys. Some of the topical corticosteroids and their metabolites are also excreted into the bile.
Betamethasone Valerate cream is indicated for the relief of the inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses.
Betamethasone Valerate cream is contraindicated in those patients with a history of hypersensitivity to any of the components of the preparation.
Systemic absorption of topical corticosteroids has produced reversible hypothalamic-pituitary-adrenal (HPA) axis suppression, manifestations of Cushing's syndrome, hyperglycemia, and glucosuria in some patients.
Conditions which augment systemic absorption include the application of the more potent steroids, use over large surface areas, prolonged use, and the addition of occlusive dressings.
Therefore, patients receiving a large dose of a potent topical steroid applied to a large surface area or under an occlusive dressing should be evaluated periodically for evidence of HPA axis suppression by using the urinary free cortisol and ACTH stimulation tests. If HPA axis suppression is noted, an attempt should be made to withdraw the drug, to reduce the frequency of application, or to substitute a less potent steroid.
Recovery of HPA axis function is generally prompt and complete upon discontinuation of the drug. Infrequently, signs and symptoms of steroid withdrawal may occur, requiring supplemental systemic corticosteroids.
Children may absorb proportionally larger amounts of topical corticosteroids and thus be more susceptible to systemic toxicity. (See PRECAUTIONS-Pediatric Use).
If irritation develops, use of Betamethasone Valerate cream should be discontinued and appropriate therapy instituted.
In the presence of dermatological infections, the use of an appropriate antifungal or antibacterial agent should be instituted. If a favorable response does not occur promptly, use of Betamethasone Valerate cream should be discontinued until the infection has been adequately controlled.
Patients using Betamethasone Valerate cream should receive the following information and instructions:
The following tests may be helpful in evaluating the HPA axis suppression:
Urinary free cortisol test
ACTH stimulation test
Long-term animal studies have not been performed to evaluate the carcinogenic potential or the effect on fertility of topical corticosteroids.
Studies to determine mutagenicity with prednisolone and hydrocortisone have revealed negative results.
Corticosteroids are generally teratogenic in laboratory animals when administered systemically at relatively low dosage levels. The more potent corticosteroids have been shown to be teratogenic after dermal application in laboratory animals. There are no adequate and well-controlled studies in pregnant women on teratogenic effects from topically applied corticosteroids. Therefore, Betamethasone Valerate cream should be used during pregnancy only if the potential benefit justifies potential risk to the fetus. Drugs of this class should not be used extensively on pregnant patients, in large amounts, or for prolonged periods of time.
It is not known whether topical administration of corticosteroids could result in sufficient systemic absorption to produce detectable quantities in breast milk. Systemically administered corticosteroids are secreted into breast milk in quantities not likely to have a deleterious effect on the infant. Nevertheless, caution should be exercised when Betamethasone Valerate cream is administered to a nursing woman.
Pediatric patients may demonstrate greater susceptibility to topical corticosteroid-induced HPA axis suppression and Cushing's syndrome than mature patients because of a larger skin surface area to body weight ratio.
Hypothalamic-pituitary-adrenal (HPA) axis suppression, Cushing's syndrome, and intracranial hypertension have been reported in children receiving topical corticosteroids. Manifestations of adrenal suppression in children include linear growth retardation, delayed weight gain, low plasma cortisol levels, and absence of response to ACTH stimulation. Manifestations of intracranial hypertension include bulging fontanelles, headaches, and bilateral papilledema.
Administration of Betamethasone Valerate cream to children should be limited to the least amount compatible with an effective therapeutic regimen. Chronic corticosteroid therapy may interfere with the growth and development of children.
The following local adverse reactions are reported infrequently with topical corticosteroids, but may occur more frequently with the use of occlusive dressings. These reactions are listed in an approximate decreasing order of occurrence:
| Burning | Hypertrichosis | Maceration of the Skin |
| Itching | Acneiform Eruptions | Secondary Infection |
| Irritation | Hypopigmentation | Skin Atrophy |
| Dryness | Perioral Dermatitis | Striae |
| Folliculitis | Allergic Contact Dermatitis | Miliaria |
Topically applied corticosteroids can be absorbed in sufficient amounts to produce systemic effects (see PRECAUTIONS).
Betamethasone Valerate Cream USP, 0.1% is generally applied to the affected skin areas one to three times daily. Dosage once or twice a day is often effective.
Occlusive dressings may be used for the management of psoriasis or recalcitrant conditions.
If an infection develops, the use of occlusive dressing should be discontinued and appropriate antimicrobial therapy instituted.
Betamethasone Valerate Cream USP, 0.1% is supplied in 15 gram (NDC 51672-1269-1) and 45 gram (NDC 51672-1269-6) tubes.
Store at 20° - 25°C (68° - 77°F) [see USP Controlled Room Temperature].
Mfd. by: Taro Pharmaceuticals Inc., Brampton, Ontario, Canada L6T 1C1
Revised: March 2005
PK-0759-4 128
NDC 51672-1269-1
15 g
Betamethasone Valerate
Cream USP, 0.1%
FOR EXTERNAL USE ONLY.
NOT FOR OPHTHALMIC USE.
Rx only
Keep this and all medications out of the reach of children.
TARO
| Betamethasone Valerate Betamethasone Valerate cream | ||||||||||||||||||||||||
| ||||||||||||||||||||||||
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| Marketing Information | |||
| Marketing Category | Application Number or Monograph Citation | Marketing Start Date | Marketing End Date |
| ANDA | ANDA072041 | 01/06/1988 | |
| Labeler - Taro Pharmaceuticals U.S.A., Inc. (145186370) |
| Establishment | |||
| Name | Address | ID/FEI | Operations |
| Taro Pharmaceuticals Inc. | 206263295 | MANUFACTURE | |
Azatrilem may be available in the countries listed below.
Azathioprine is reported as an ingredient of Azatrilem in the following countries:
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Enalapril/Hydrochlorothiazide RPG may be available in the countries listed below.
Enalapril maleate (a derivative of Enalapril) is reported as an ingredient of Enalapril/Hydrochlorothiazide RPG in the following countries:
Hydrochlorothiazide is reported as an ingredient of Enalapril/Hydrochlorothiazide RPG in the following countries:
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Romyk may be available in the countries listed below.
Roxithromycin is reported as an ingredient of Romyk in the following countries:
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Generic Name: dapsone (DAP sone)
Brand Names:
Dapsone is an antiinfective medication.
Dapsone is used in the treatment of dermatitis herpetiformis (a skin condition) and leprosy (Hansen's disease).
Dapsone may also be used for purposes other than those listed in this medication guide.
glucose 6-phosphate dehydrogenase (G6PD) deficiency;
methemoglobin reductase deficiency (hemoglobin M); or
You may not be able to take dapsone, or you may require a dosage adjustment or special monitoring if you have any of the conditions listed above.
Take dapsone exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.
Taking dapsone with food may decrease stomach upset, should it occur.
It is important to take dapsone regularly to get the most benefit.
Your doctor may want you to have blood tests or other forms of monitoring during treatment with dapsone.
See also: Dapsone dosage (in more detail)
Take the missed dose as soon as you remember. If it is almost time for the next dose, skip the dose you missed and take only the next regularly scheduled dose. Do not take a double dose of this medication, unless otherwise directed by your doctor.
Symptoms of a dapsone overdose may include nausea, vomiting, excitation, seizures, and bluish skin color.
an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);
bluish skin color;
muscle weakness;
numbness or tingling;
abdominal pain;
difficulty breathing;
dark colored urine or pale colored stools; or
unusual tiredness.
Other, less serious side effects may be more likely to occur. Notify your doctor if you experience
nausea or vomiting;
blurred vision;
ringing in the ears;
headache;
insomnia; or
increased sensitivity of the skin to sunlight.
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.
Usual Adult Dose for Leprosy -- Lepromatous:
50 to 100 mg orally once a day for 2-5 years.
Usual Adult Dose for Leprosy -- Tuberculoid:
100 mg orally once a day for 6 months. Rifampin is additionally recommended to reduce the incidence of dapsone resistance. If the disease relapses, this regimen should be repeated.
Usual Adult Dose for Dermatitis Herpetiformis:
50 mg orally once a day continued on a life-long basis. Dosage may be advanced to 300 mg/day. Dosage reduction to a minimum maintenance level as soon as possible is recommended.
Usual Adult Dose for Pneumocystis Pneumonia:
100 mg orally once a day for 14 to 21 days. Used in combination with trimethoprim.
Usual Adult Dose for Pneumocystis Pneumonia Prophylaxis:
100 mg orally twice a week. Therapy should be continued on a life-long basis. The addition of pyrimethamine appears to significantly increase the activity of dapsone for PCP prophylaxis.
Usual Adult Dose for Toxoplasmosis -- Prophylaxis:
100 mg orally twice a week continued on a life-long basis.
Usual Pediatric Dose for Leprosy:
1 to 2 mg/kg (up to 100 mg) orally once a day.
Usual Pediatric Dose for Pneumocystis Pneumonia Prophylaxis:
> 1 month:
2 mg/kg/day (up to 100 mg) orally once a day.
Alternate dosing:
> 1 month:
4 mg/kg orally once weekly. Maximum dose = 200 mg.
Usual Pediatric Dose for Toxoplasmosis -- Prophylaxis:
> 1 month:
2 mg/kg/day (or 15 mg/m2) orally once a day. Maximum dose = 25 mg. Dapsone should be administered as part of combination therapy for prophylaxis of toxoplasmosis.
Many other drugs can interact with dapsone, especially those that may also affect the blood. Do not take any other prescription or over-the-counter medicines, including vitamins, minerals, and herbal products, during treatment with dapsone without first talking to your doctor.
Adiuvan may be available in the countries listed below.
Glimepiride is reported as an ingredient of Adiuvan in the following countries:
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Benazepril comp. Heumann may be available in the countries listed below.
Benazepril hydrochloride (a derivative of Benazepril) is reported as an ingredient of Benazepril comp. Heumann in the following countries:
Hydrochlorothiazide is reported as an ingredient of Benazepril comp. Heumann in the following countries:
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Ocean Gold may be available in the countries listed below.
In some countries, this medicine may only be approved for veterinary use.
Colecalciferol is reported as an ingredient of Ocean Gold in the following countries:
Retinol is reported as an ingredient of Ocean Gold in the following countries:
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Lucenfal may be available in the countries listed below.
Nicardipine hydrochloride (a derivative of Nicardipine) is reported as an ingredient of Lucenfal in the following countries:
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Pexal may be available in the countries listed below.
Pentoxifylline is reported as an ingredient of Pexal in the following countries:
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There are currently no drugs listed for "Constrictive Pericarditis".
Definition of Constrictive Pericarditis: Constrictive pericarditis is a disorder caused by inflammation of the pericardium (the sac-like covering of the heart) with subsequent thickening, scarring, and contracture of the pericardium.
Micromedex Care Notes:
Medical Encyclopedia:
Allercet may be available in the countries listed below.
Cetirizine dihydrochloride (a derivative of Cetirizine) is reported as an ingredient of Allercet in the following countries:
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Omniflox may be available in the countries listed below.
Sparfloxacin is reported as an ingredient of Omniflox in the following countries:
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Diclofenaco Aldo Union may be available in the countries listed below.
Diclofenac sodium salt (a derivative of Diclofenac) is reported as an ingredient of Diclofenaco Aldo Union in the following countries:
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Rec.INN
C04AX20
0055837-25-7
C17-H25-N-O4
307
Vasodilator, peripheric
1-Butanone, 4-(1-pyrrolidinyl)-1-(2,4,6-trimethoxyphenyl)-
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Glossary
| BAN | British Approved Name |
| BANM | British Approved Name (Modified) |
| DCF | Dénomination Commune Française |
| DCIT | Denominazione Comune Italiana |
| IS | Inofficial Synonym |
| OS | Official Synonym |
| PH | Pharmacopoeia Name |
| Rec.INN | Recommended International Nonproprietary Name (World Health Organization) |
Norset may be available in the countries listed below.
Mirtazapine is reported as an ingredient of Norset in the following countries:
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Métronidazole Baxter may be available in the countries listed below.
Metronidazole is reported as an ingredient of Métronidazole Baxter in the following countries:
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Etopan may be available in the countries listed below.
Etodolac is reported as an ingredient of Etopan in the following countries:
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Brietal may be available in the countries listed below.
Methohexital sodium salt (a derivative of Methohexital) is reported as an ingredient of Brietal in the following countries:
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Maprotilin Mylan may be available in the countries listed below.
Maprotiline hydrochloride (a derivative of Maprotiline) is reported as an ingredient of Maprotilin Mylan in the following countries:
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Pantoprazol STADA may be available in the countries listed below.
Pantoprazole is reported as an ingredient of Pantoprazol STADA in the following countries:
Pantoprazole sodium (a derivative of Pantoprazole) is reported as an ingredient of Pantoprazol STADA in the following countries:
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In the US, Triesence (triamcinolone ophthalmic) is a member of the drug class ophthalmic steroids and is used to treat Temporal Arteritis, Uveitis and Vitrectomy.
US matches:
Triamcinolone 16α,17α-acetonide (a derivative of Triamcinolone) is reported as an ingredient of Triesence in the following countries:
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Generic Name: dyphylline (dye FI lin)
Brand names: Dilor, Dylix, Lufyllin, Neothylline, Lufyllin-400, Dilor-400
Dyphylline is a bronchodilator. Dyphylline works in several ways: It relaxes muscles in your lungs and chest to allow more air in, it decreases the sensitivity of your lungs to allergens and other substances that cause inflammation, and it increases the contractions of your diaphragm to draw more air into the lungs.
Dyphylline is used to treat the symptoms of asthma, bronchitis, and emphysema.
Dyphylline may also be used for purposes other than those listed in this medication guide.
Call your doctor right away if you experience nausea, vomiting, insomnia, restlessness, seizures, an increased heart rate, or a headache. These could be signs of too much dyphylline in your blood.
Do not start or stop smoking without your doctor's knowledge. Smoking may affect your dosage.
Do not take more of this medicine than is prescribed without consulting your doctor. Seek medical attention if you are having increasing difficulty breathing.
Before taking this medication, tell your doctor if you have
a stomach ulcer;
seizures;
high blood pressure, a heart condition, or any type of heart disease;
fluid in your lungs;
a thyroid condition;
liver disease; or
kidney disease.
You may not be able to take dyphylline, or you may require a lower dose or special monitoring during treatment if you have any of the conditions listed above.
Take dyphylline exactly as directed by your doctor. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.
Take your doses at the same time every day to keep a constant level of dyphylline in your blood.
Do not switch to another brand or a generic form of dyphylline without the approval of your doctor.
Take the missed dose as soon as you remember. However, if it is almost time for your next regularly scheduled dose, skip the missed dose and take the next one as directed. Do not take a double dose of this medication.
Symptoms of a dyphylline overdose include nausea, vomiting, headache, insomnia, tremor (shaking hands or twitching,), restlessness, seizures, and irregular heartbeats.
Do not start or stop smoking without the approval of your doctor. Smoking changes the way your body uses dyphylline, and you may need a dose adjustment.
Avoid changing your dose or changing the time of your daily doses.
Do not change the brand, generic form, or formulation (tablet, capsule, liquid) of dyphylline that you are taking without the approval of your doctor. Different brands or formulations may require different dosages.
Avoid eating excessive amounts of grilled or char-broiled foods. Doing so may also change the dose of dyphylline that you need.
an allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives);
seizures;
increased or irregular heartbeats; or
severe nausea or vomiting.
Other, less serious side effects may occur although they are not common at appropriate doses. Continue to take dyphylline and talk to your doctor if you experience
slight nausea, decreased appetite, or weight loss;
restlessness, tremor, or insomnia; or
headache, lightheadedness, or dizziness.
Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome. You may report side effects to FDA at 1-800-FDA-1088.
Dyphylline interacts with many other drugs. Tell your doctor and pharmacist about all other medications that you are taking, including herbal remedies, vitamins, and other nonprescription items.
The following drugs may increase the levels of dyphylline in your blood, leading to dangerous side effects:
alcohol;
cimetidine (Tagamet, Tagamet HB);
fluoroquinolone antibiotics such as enoxacin (Penetrex), lomefloxacin (Maxaquin), ciprofloxacin (Cipro), norfloxacin (Noroxin), and ofloxacin (Floxin);
clarithromycin (Biaxin) and erythromycin (Ery-Tab, E.E.S., E-Mycin, others);
disulfiram (Antabuse);
estrogens (Ogen, Premarin, and many other types);
fluvoxamine (Luvox);
methotrexate (Folex, Rheumatrex);
mexiletine (Mexitil) and propafenone (Rythmol);
propranolol (Inderal);
tacrine (Cognex);
ticlopidine (Ticlid); and
verapamil (Verelan, Calan, Isoptin).
The following drugs may decrease dyphylline levels in your blood, leading to poor asthma control:
aminoglutethimide (Cytadren),
carbamazepine (Tegretol),
isoproterenol (Isuprel),
moricizine (Ethmozine),
phenobarbital (Luminal, Solfoton),
phenytoin (Dilantin),
rifampin (Rifadin), and
sucralfate (Carafate).
Drugs other than those listed here may also interact with dyphylline or affect your condition. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines.
See also: dyphylline side effects (in more detail)
Relieving symptoms of sinus congestion, pressure, runny nose, and sneezing due to colds, upper respiratory infections, and allergies. It may also be used for other conditions as determined by your doctor.
Diphenhydramine/Pseudoephedrine is an antihistamine and decongestant combination. The antihistamine works by blocking the action of histamine, which helps reduce symptoms such as watery eyes and sneezing. The decongestant works by promoting sinus and nasal drainage, which relieves congestion and pressure.
Contact your doctor or health care provider right away if any of these apply to you.
Some medical conditions may interact with Diphenhydramine/Pseudoephedrine. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:
Some MEDICINES MAY INTERACT with Diphenhydramine/Pseudoephedrine. Tell your health care provider if you are taking any other medicines, especially any of the following:
This may not be a complete list of all interactions that may occur. Ask your health care provider if Diphenhydramine/Pseudoephedrine may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.
Use Diphenhydramine/Pseudoephedrine as directed by your doctor. Check the label on the medicine for exact dosing instructions.
Ask your health care provider any questions you may have about how to use Diphenhydramine/Pseudoephedrine.
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Constipation; diarrhea; dizziness; drowsiness; dry mouth, nose, and throat; excitability; headache; loss of appetite; nausea; nervousness or anxiety; trouble sleeping; upset stomach; vomiting; weakness.
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blurred vision or other vision changes; fast or irregular heartbeat; fever, chills, or persistent sore throat; hallucinations; mood or mental changes; persistent trouble sleeping; restlessness; seizures; severe dizziness, lightheadedness, or headache; severe drowsiness; tremor; trouble urinating or inability to urinate; unusual bruising or bleeding.
This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.
See also: Diphenhydramine/Pseudoephedrine side effects (in more detail)
Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include blurred vision; confusion; hallucinations; ringing in the ears; seizures; severe dizziness, lightheadedness, or headache; severe drowsiness; unusually fast, slow, or irregular breathing; unusually fast, slow, or irregular heartbeat.
Store Diphenhydramine/Pseudoephedrine at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Diphenhydramine/Pseudoephedrine out of the reach of children and away from pets.
This information is a summary only. It does not contain all information about Diphenhydramine/Pseudoephedrine. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.
Laurimic Vaginal may be available in the countries listed below.
Fenticonazole nitrate (a derivative of Fenticonazole) is reported as an ingredient of Laurimic Vaginal in the following countries:
International Drug Name Search
Fludarabinphosphat Pharmachemie may be available in the countries listed below.
Fludarabine phosphate (a derivative of Fludarabine) is reported as an ingredient of Fludarabinphosphat Pharmachemie in the following countries:
International Drug Name Search
Maleato de Timolol may be available in the countries listed below.
Timolol maleate (a derivative of Timolol) is reported as an ingredient of Maleato de Timolol in the following countries:
International Drug Name Search
Cetirizine Teva may be available in the countries listed below.
Cetirizine dihydrochloride (a derivative of Cetirizine) is reported as an ingredient of Cetirizine Teva in the following countries:
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Natriumvalproaat Sandoz may be available in the countries listed below.
Valproic Acid sodium (a derivative of Valproic Acid) is reported as an ingredient of Natriumvalproaat Sandoz in the following countries:
International Drug Name Search
Nobritol may be available in the countries listed below.
Amitriptyline hydrochloride (a derivative of Amitriptyline) is reported as an ingredient of Nobritol in the following countries:
Medazepam is reported as an ingredient of Nobritol in the following countries:
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Veranorm may be available in the countries listed below.
Verapamil hydrochloride (a derivative of Verapamil) is reported as an ingredient of Veranorm in the following countries:
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Nicorax may be available in the countries listed below.
Carvedilol is reported as an ingredient of Nicorax in the following countries:
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Doxorrubicina Farma-Aps may be available in the countries listed below.
Doxorubicin is reported as an ingredient of Doxorrubicina Farma-Aps in the following countries:
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Serenamin may be available in the countries listed below.
Diazepam is reported as an ingredient of Serenamin in the following countries:
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Fluorogel may be available in the countries listed below.
Sodium Fluoride is reported as an ingredient of Fluorogel in the following countries:
International Drug Name Search
Generic Name: oxycodone (Oral route)
ox-i-KOE-done hye-droe-KLOR-ide
Oxycodone hydrochloride is an opioid agonist and a Schedule II controlled substance with an abuse potential similar to morphine. Patients should be assessed for their clinical risks for opioid abuse or addiction prior to being prescribed opioids. Oxycodone hydrochloride controlled-release tablets are indicated for continuous, around the clock analgesia for an extended period of time; not for use on an as needed basis. The 60 mg and 80 mg tablets, a single dose greater than 40 mg, or a total daily dose greater than 80 mg, are only for use in opioid-tolerant patients as they may cause fatal respiratory depression when administered to patients who are not tolerant to the respiratory depressant effects of opioids. Oxycodone hydrochloride controlled-release tablets must be swallowed whole to avoid a rapid release of the drug which can be potentially fatal. Concomitant use with CYP3A4 inhibitors may result in an increase in oxycodone plasma concentrations and may cause potentially fatal respiratory depression .
In the U.S.
In Canada
Available Dosage Forms:
Therapeutic Class: Analgesic
Chemical Class: Oxycodone
Oxycodone is used to relieve moderate to severe pain. It belongs to the group of medicines called narcotic analgesics (pain medicines). Oxycodone acts on the central nervous system (CNS) to relieve pain.
When oxycodone is used for a long time, it may become habit-forming, causing mental or physical dependence. However, people who have continuing pain should not let the fear of dependence keep them from using narcotics to relieve their pain. Mental dependence (addiction) is not likely to occur when narcotics are used for this purpose. Physical dependence may lead to withdrawal side effects if treatment is stopped suddenly. However, severe withdrawal side effects can usually be prevented by gradually reducing the dose over a period of time before treatment is stopped completely.
This medicine is available only with your doctor's prescription.
In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:
Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.
Appropriate studies have not been performed on the relationship of age to the effects of oxycodone in the pediatric population. Safety and efficacy have not been established.
Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of oxycodone in the elderly. However, elderly patients are more likely to have age-related liver or kidney problems, which may require caution and an adjustment in the dose for patients receiving oxycodone.
| Pregnancy Category | Explanation | |
|---|---|---|
| All Trimesters | B | Animal studies have revealed no evidence of harm to the fetus, however, there are no adequate studies in pregnant women OR animal studies have shown an adverse effect, but adequate studies in pregnant women have failed to demonstrate a risk to the fetus. |
Studies in women breastfeeding have demonstrated harmful infant effects. An alternative to this medication should be prescribed or you should stop breastfeeding while using this medicine.
Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. When you are taking this medicine, it is especially important that your healthcare professional know if you are taking any of the medicines listed below. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.
Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Using this medicine with any of the following medicines may cause an increased risk of certain side effects, but using both drugs may be the best treatment for you. If both medicines are prescribed together, your doctor may change the dose or how often you use one or both of the medicines.
Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.
Using this medicine with any of the following is usually not recommended, but may be unavoidable in some cases. If used together, your doctor may change the dose or how often you use this medicine, or give you special instructions about the use of food, alcohol, or tobacco.
The presence of other medical problems may affect the use of this medicine. Make sure you tell your doctor if you have any other medical problems, especially:
This section provides information on the proper use of a number of products that contain oxycodone. It may not be specific to Oxyfast. Please read with care.
Take this medicine only as directed by your doctor. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. This is especially important for elderly patients, who may be more sensitive to the effects of pain medicines. If too much of this medicine is taken for a long time, it may become habit-forming (causing mental or physical dependence).
This medicine comes with a patient information leaflet. Read and follow these instructions carefully. Ask your doctor if you have any questions.
Oxycodone extended-release tablets should only be used by patients who have already been taking narcotic pain medicines, also called opioids. These patients are called opioid-tolerant. If you are uncertain whether or not you are opioid-tolerant, check with your doctor before using this medicine.
Measure the oral liquid concentrate with the calibrated dropper that comes with the package. Your doctor may have you mix the concentrate with a small amount of liquid or food. Carefully follow the instructions and take the medicine mixture right away.
Measure the oral liquid with a marked measuring spoon, oral syringe, or medicine cup. The average household teaspoon may not hold the right amount of liquid.
Swallow the Oxecta® or OxyContin® tablet whole with water. Do not break, crush, cut, chew, or dissolve it. Do not pre-soak, lick, or wet the tablet before placing it in the mouth. Take one tablet at a time. Also, do not give this medicine through nasogastric or feeding tubes.
Oxycodone extended-release tablets work differently from the regular oxycodone oral solution or tablets, even at the same dose. Do not switch from one brand or form to the other unless your doctor tells you to.
The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.
The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.
If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.
Keep out of the reach of children.
Do not keep outdated medicine or medicine no longer needed.
Ask your healthcare professional how you should dispose of any medicine you do not use.
Oxycodone can cause serious unwanted effects if taken by adults who are not used to strong narcotic pain medicines, children, or pets. Make sure you store the medicine in a safe and secure place to prevent others from getting it.
Flush the unused extended-release tablets and immediate-release tablets down the toilet.
It is very important that your doctor check your progress while you are taking this medicine. This will allow your doctor to see if the medicine is working properly and to decide if you should continue to take it.
This medicine will add to the effects of alcohol and other CNS depressants (medicines that can make you drowsy or less alert). Some examples of CNS depressants are antihistamines or medicine for allergies or colds; sedatives, tranquilizers, or sleeping medicine; other prescription pain medicine or narcotics; medicine for seizures or barbiturates; muscle relaxants; or anesthetics, including some dental anesthetics. Check with your doctor before taking any of these medicines while you are using this medicine.
This medicine may be habit-forming. If you feel that the medicine is not working as well, do not use more than your prescribed dose. Call your doctor for instructions.
Dizziness, lightheadedness, or fainting may occur when you get up suddenly from a lying or sitting position. Getting up slowly may help lessen this problem. Also, lying down for a while may relieve the dizziness or lightheadedness.
This medicine may make you dizzy, drowsy, or lightheaded. Make sure you know how you react to this medicine before you drive, use machines, or do anything else that could be dangerous if you are dizzy or not alert.
Using narcotics for a long time can cause severe constipation. To prevent this, your doctor may direct you to take laxatives, drink a lot of fluids, or increase the amount of fiber in your diet. Be sure to follow the directions carefully, because continuing constipation can lead to more serious problems.
If you have been using this medicine regularly for several weeks or longer, do not change your dose or suddenly stop using it without checking with your doctor. Your doctor may want you to gradually reduce the amount you are using before stopping it completely. This may help prevent worsening of your condition and reduce the possibility of withdrawal symptoms, such as abdominal or stomach cramps, anxiety, fever, nausea, runny nose, sweating, tremors, or trouble with sleeping.
Using this medicine while you are pregnant may cause serious unwanted effects in your newborn baby. Tell your doctor right away if you think you are pregnant or if you plan to become pregnant while using this medicine.
Do not take other medicines unless they have been discussed with your doctor. This includes prescription or nonprescription (over-the-counter [OTC]) medicines and herbal or vitamin supplements.
Along with its needed effects, a medicine may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur:
Get emergency help immediately if any of the following symptoms of overdose occur:
Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.
Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.
See also: Oxyfast side effects (in more detail)
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