Meclizine Chewable Tablets

Pronunciation: MEK-li-zeen
Generic Name: Meclizine
Brand Name: Travel-Ease

Meclizine Chewable Tablets are used for:

Preventing and treating nausea, vomiting, and dizziness associated with motion sickness. It may also be used for other conditions as determined by your doctor.

Meclizine Chewable Tablets are an anticholinergic. It works by blocking a chemical messenger that is activating the vomiting center and thus prevents or reduces nausea and vomiting due to motion.

Do NOT use Meclizine Chewable Tablets if:

• you are allergic to any ingredient in Meclizine Chewable Tablets


• you are taking sodium oxybate (GHB) or you drink alcohol

Contact your doctor or health care provider right away if any of these apply to you.

Before using Meclizine Chewable Tablets:

Some medical conditions may interact with Meclizine Chewable Tablets. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have asthma; chronic obstructive pulmonary disease (COPD); chronic bronchitis, or emphysema; blockage of the stomach, intestine, or urinary tract;enlargement of the prostate; or glaucoma

Some MEDICINES MAY INTERACT with Meclizine Chewable Tablets. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Ethanol or sodium oxybate (GHB) because an increase in sleep duration and a decrease in the ability to breathe are likely to occur

This may not be a complete list of all interactions that may occur. Ask your health care provider if Meclizine Chewable Tablets may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Meclizine Chewable Tablets:

Use Meclizine Chewable Tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Meclizine Chewable Tablets by mouth with or without food.


• Meclizine Chewable Tablets may be chewed or swallowed whole.


• For prevention of motion sickness, take Meclizine Chewable Tablets at least 1 hour before activity or travel.


• If you miss a dose of Meclizine Chewable Tablets and you are using it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Meclizine Chewable Tablets.

Important safety information:

• Meclizine Chewable Tablets may cause drowsiness or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Meclizine Chewable Tablets with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.


• Do not drink alcohol or use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Meclizine Chewable Tablets; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.


• This product may contain tartrazine dye (FD&C Yellow No. 5). This may cause an allergic reaction in some patients. If you have ever had an allergic reaction to tartrazine, ask your pharmacist if your product has tartrazine in it.


• Meclizine Chewable Tablets should not be used in CHILDREN younger than 12 years old; safety and effectiveness in these children have not been confirmed.


• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Meclizine Chewable Tablets while you are pregnant. It is unknown if Meclizine Chewable Tablets are found in breast milk. If you are or will be breast-feeding while you use Meclizine Chewable Tablets, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Meclizine Chewable Tablets:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Drowsiness; dry mouth.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue).

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Meclizine side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include drowsiness; hallucinations; seizures; unusual excitability; very slow or shallow breathing.

Proper storage of Meclizine Chewable Tablets:

Store at room temperature, below 86 degrees F (30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Meclizine Chewable Tablets out of the reach of children and away from pets.

General information:

• If you have any questions about Meclizine Chewable Tablets, please talk with your doctor, pharmacist, or other health care provider.


• Meclizine Chewable Tablets are to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Meclizine Chewable Tablets. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Meclizine resources

• Meclizine Side Effects (in more detail)
• Meclizine Dosage
• Meclizine Use in Pregnancy & Breastfeeding
• Drug Images
• Meclizine Drug Interactions
• Meclizine Support Group
• 47 Reviews for Meclizine - Add your own review/rating

Compare Meclizine with other medications

• Motion Sickness
• Nausea/Vomiting
• Vertigo

Adagen

Generic Name: pegademase bovine (peg AD e mase BOE vine)

Brand Names: Adagen

What are Adagen (pegademase bovine)?

Pegademase bovine is the enzyme called adenosine deaminase (ADA). Without ADA, certain proteins accumulate that harm white blood cells. White blood cells are important for protecting the body from infection.

Pegademase bovine is used to replenish ADA which allows an increase in white blood cells and decreases the risk of infection in conditions such as severe combined immunodeficiency disease (SCID).

Pegademase bovine may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about Adagen (pegademase bovine)?

Do not administer an injection if you are unsure how to properly do so, how much to inject, or how often to inject the medication. Call your doctor, nurse, or pharmacist to go over the instructions with you. Contact your doctor if you develop a fever; chills; sore throat; congestion; or redness, pain, or swelling around a wound or sore while using pegademase bovine. These may be signs of infection.

What should I discuss with my healthcare provider before using a Adagen (pegademase bovine)?

Before using pegademase bovine, tell your doctor if you

• 
  

  are undergoing radiation or receiving chemotherapy; or

  
  


• 
  

  have a bleeding disorder.

  
  

You may not be able to use pegademase bovine or you may require a dosage adjustment or special monitoring if you have any of the conditions listed above.

Pegademase bovine is in the FDA pregnancy category C. This means that it is not known whether pegademase bovine will be harmful to an unborn baby. Do not use pegademase bovine without first talking to your doctor if you are pregnant or could become pregnant during treatment. It is not known whether pegademase bovine will be harmful to a nursing baby. Do not use pegademase bovine without first talking to your doctor if you are breast-feeding a baby.

How should I use Adagen (pegademase bovine)?

Use pegademase bovine exactly as directed by your doctor. If you do not understand these instructions, ask your pharmacist, nurse, or doctor to explain them to you.

Pegademase bovine is given by intramuscular (IM) injection. Your doctor, nurse, or pharmacist will give you specific instructions on how and where to inject the medication.

Do not administer an injection if you are unsure how to properly do so, how much to inject, or how often to inject the medication. Call your doctor, nurse, or pharmacist to go over the instructions with you.

Pegademase bovine is usually administered once every 7 days.

Do not inject a pegademase bovine that is discolored or that has particles in it.

Properly store and discard all syringes and needles.

Your doctor may want you to have regularly scheduled blood tests while using pegademase bovine to monitor effectiveness and possible side effects of the medication.

Do not stop taking pegademase bovine without talking to your doctor. It may take several weeks to 6 months to be fully effective. Stopping pegademase bovine may cause your immune system to become less effective and serious infections may occur.

Store pegademase bovine in the refrigerator between 2 and 8 degrees Celsius (36 to 46 degrees Fahrenheit) away from light, moisture, and the reach of children. Avoid freezing the medication. Do not use this product if there are any indications that it may have frozen.

What happens if I miss a dose?

Contact your doctor as soon as possible if you miss a dose of this medication.

What happens if I overdose?

Seek emergency medical attention.

Symptoms of a pegademase bovine overdose are not known.

What should I avoid while using Adagen (pegademase bovine)?

There are no restrictions regarding foods, beverages, or activities during treatment with pegademase bovine unless otherwise directed by your doctor.

Adagen (pegademase bovine) side effects

If you experience any of the following serious side effects, stop using the pegademase bovine and seek emergency medical treatment or contact your doctor immediately:

• 
  

  an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives); or

  
  


• 
  

  signs of infection such as sore throat, fever or congestion.

  
  

Other, less serious side effects may be more likely to occur. Continue to use the pegademase bovine and talk to your doctor if you experience:

• 
  

  headache;

  
  


• 
  

  swelling, redness, or pain at the injection site.

  
  

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Adagen (pegademase bovine)?

Before using this medication, tell your doctor if you

• 
  

  are receiving vidarabine eye ointment (Vira-A).

  
  

You may not be able to use the pegademase bovine or you may require a dosage adjustment or special monitoring if you are taking the medication listed above.

Drugs other than those listed here may also interact with pegademase bovine. Talk to your doctor and pharmacist before taking any prescription or over-the-counter medicines, including herbal products.

More Adagen resources

• Adagen Side Effects (in more detail)
• Adagen Use in Pregnancy & Breastfeeding
• Adagen Drug Interactions
• Adagen Support Group
• 0 Reviews for Adagen - Add your own review/rating

• Adagen Prescribing Information (FDA)


• Adagen Advanced Consumer (Micromedex) - Includes Dosage Information


• Adagen MedFacts Consumer Leaflet (Wolters Kluwer)

Compare Adagen with other medications

• Immunodeficiency

Where can I get more information?

• Your pharmacist can provide more information about pegademase bovine.

See also: Adagen side effects (in more detail)

Nizoral A-D Shampoo

Pronunciation: kee-toe-KOE-na-zole
Generic Name: Ketoconazole
Brand Name: Nizoral A-D

Nizoral A-D Shampoo is used for:

Treating scaling associated with dandruff. It may also be used for other conditions as determined by your doctor.

Nizoral A-D Shampoo is an imidazole antifungal. It works by killing sensitive fungi by interfering with the formation of the fungal cell membrane and weakening it. The weakened cell membrane allows the cell contents to leak out and results in the death of the fungus.

Do NOT use Nizoral A-D Shampoo if:

• you are allergic to any ingredient in Nizoral A-D Shampoo

Contact your doctor or health care provider right away if any of these apply to you.

Before using Nizoral A-D Shampoo:

Some medical conditions may interact with Nizoral A-D Shampoo. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have low blood sugar levels, liver disease, or porphyria (a blood disease), sulfite sensitivity, or you drink more than 3 alcohol-containing drinks a day

Some MEDICINES MAY INTERACT with Nizoral A-D Shampoo. Because little, if any, of Nizoral A-D Shampoo is absorbed into the blood, the risk of it interacting with another medicine is low.

Ask your health care provider if Nizoral A-D Shampoo may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Nizoral A-D Shampoo:

Use Nizoral A-D Shampoo as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Moisten hair and scalp with water. Apply enough shampoo to wash your scalp and hair. Gently massage the entire scalp, leaving the shampoo on for about 5 minutes. Rinse thoroughly, then dry your hair as you normally do.


• Keep Nizoral A-D Shampoo out of your eyes, nose, and mouth. If this occurs, wash with water and contact your doctor, nurse, or pharmacist.


• If you miss a dose of Nizoral A-D Shampoo, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Nizoral A-D Shampoo.

Important safety information:

• Be sure to use Nizoral A-D Shampoo for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.


• If you use topical products too often, your condition may become worse.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Some of these products contain sulfites. Sulfites may cause an allergic reaction in some patients (eg, asthma patients). If you have ever had an allergic reaction to sulfites, ask your pharmacist if your product has sulfites in it.


• Talk to your doctor before you take Nizoral A-D Shampoo if you drink more than 3 drinks with alcohol per day.


• Using Nizoral A-D Shampoo on hair that has been permanently waved may cause a loss of the curl.


• Nizoral A-D Shampoo should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.


• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Nizoral A-D Shampoo while you are pregnant. If you are or will be breast-feeding while you use Nizoral A-D Shampoo, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Nizoral A-D Shampoo:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Itching; mild irritation or stinging; oiliness and dryness of hair and scalp.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); increased or abnormal hair loss; reddening, blistering, peeling, itching, or burning of your skin.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Nizoral A-D side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of Nizoral A-D Shampoo:

Store Nizoral A-D Shampoo between 59 and 77 degrees F (15 and 25 degrees C). Store in a tightly closed container. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Nizoral A-D Shampoo out of the reach of children and away from pets.

General information:

• If you have any questions about Nizoral A-D Shampoo, please talk with your doctor, pharmacist, or other health care provider.


• Nizoral A-D Shampoo is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Nizoral A-D Shampoo. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Nizoral A-D resources

• Nizoral A-D Side Effects (in more detail)
• Nizoral A-D Use in Pregnancy & Breastfeeding
• Nizoral A-D Support Group
• 1 Review for Nizoral A-D - Add your own review/rating

Compare Nizoral A-D with other medications

• Cutaneous Candidiasis
• Dandruff
• Seborrheic Dermatitis
• Tinea Corporis
• Tinea Cruris
• Tinea Pedis
• Tinea Versicolor

Allegra ODT Orally Disintegrating Tablets

Pronunciation: FEX-oh-FEN-a-deen
Generic Name: Fexofenadine
Brand Name: Allegra ODT

Allegra ODT Orally Disintegrating Tablets are used for:

Treating seasonal allergy symptoms such as sneezing, runny nose, itchy throat, or itchy, watery eyes. It is also used to treat hives and skin itching. It may also be used for other conditions as determined by your doctor.

Allegra ODT Orally Disintegrating Tablets are an antihistamine. It works by blocking a substance in the body called histamine. This helps to decrease allergy symptoms.

Do NOT use Allegra ODT Orally Disintegrating Tablets if:

• you are allergic to any ingredient in Allegra ODT Orally Disintegrating Tablets

Contact your doctor or health care provider right away if any of these apply to you.

Before using Allegra ODT Orally Disintegrating Tablets:

Some medical conditions may interact with Allegra ODT Orally Disintegrating Tablets. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have kidney problems or trouble urinating


• if you have phenylketonuria (PKU)

Some MEDICINES MAY INTERACT with Allegra ODT Orally Disintegrating Tablets. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Erythromycin or ketoconazole because they may increase the risk of Allegra ODT Orally Disintegrating Tablets's side effects

This may not be a complete list of all interactions that may occur. Ask your health care provider if Allegra ODT Orally Disintegrating Tablets may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Allegra ODT Orally Disintegrating Tablets:

Use Allegra ODT Orally Disintegrating Tablets as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Allegra ODT Orally Disintegrating Tablets by mouth on an empty stomach at least 1 hour before or 2 hours after eating.


• Do not remove the medicine from the blister pack until you are ready to take it. Make sure that your hands are dry when you open the blister pack. Do not push the tablet through the foil. Peel back the foil on the blister pack and place the tablet on your tongue. The tablet dissolves quickly and can be swallowed with saliva. Allegra ODT Orally Disintegrating Tablets may be taken with or without water. Take the tablet immediately after opening the blister pack. Do not store the removed tablet for future use.


• Do not drink fruit juice at the same time that you take Allegra ODT Orally Disintegrating Tablets. Certain fruit juices (eg, grapefruit, apple, orange) may decrease Allegra ODT Orally Disintegrating Tablets's effectiveness.


• If you take antacids that contain aluminum or magnesium, do not take them at the same time as Allegra ODT Orally Disintegrating Tablets. Ask your doctor or pharmacist how to take them with Allegra ODT Orally Disintegrating Tablets.


• If you miss a dose of Allegra ODT Orally Disintegrating Tablets, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Allegra ODT Orally Disintegrating Tablets.

Important safety information:

• Allegra ODT Orally Disintegrating Tablets may cause dizziness. It does not usually cause drowsiness when used under normal circumstances at the recommended doses. However, these effects may be worse if you take Allegra ODT Orally Disintegrating Tablets with alcohol or certain medicines. Use Allegra ODT Orally Disintegrating Tablets with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.


• Do NOT take more than the recommended dose or use for longer than prescribed without checking with your doctor.


• Some of these products contain phenylalanine. If you must have a diet that is low in phenylalanine, ask your pharmacist if it is in your product.


• Allegra ODT Orally Disintegrating Tablets may interfere with skin allergy tests. If you are scheduled for a skin test, talk to your doctor. You may need to stop taking Allegra ODT Orally Disintegrating Tablets for a few days before the tests.


• Use Allegra ODT Orally Disintegrating Tablets with caution in the ELDERLY; they may be more sensitive to its effects.


• Allegra ODT Orally Disintegrating Tablets should be used with extreme caution in CHILDREN younger than 6 months old; safety and effectiveness in these children have not been confirmed.


• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Allegra ODT Orally Disintegrating Tablets while you are pregnant. It is not known if Allegra ODT Orally Disintegrating Tablets are found in breast milk. If you are or will be breast-feeding while you use Allegra ODT Orally Disintegrating Tablets, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Allegra ODT Orally Disintegrating Tablets:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Dizziness; headache; stomach upset.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); earache; fever; severe or persistent coughing or vomiting.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Allegra ODT side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include unusual or severe dizziness, drowsiness, or dry mouth.

Proper storage of Allegra ODT Orally Disintegrating Tablets:

Store Allegra ODT Orally Disintegrating Tablets between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Store in original packaging until just before use. Keep Allegra ODT Orally Disintegrating Tablets out of the reach of children and away from pets.

General information:

• If you have any questions about Allegra ODT Orally Disintegrating Tablets, please talk with your doctor, pharmacist, or other health care provider.


• Allegra ODT Orally Disintegrating Tablets are to be used only by the patient for whom it is prescribed. Do not share it with other people.


• Carry an identification card at all times that says you are taking Allegra ODT Orally Disintegrating Tablets.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Allegra ODT Orally Disintegrating Tablets. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Allegra ODT resources

• Allegra ODT Side Effects (in more detail)
• Allegra ODT Use in Pregnancy & Breastfeeding
• Allegra ODT Drug Interactions
• Allegra ODT Support Group
• 1 Review for Allegra ODT - Add your own review/rating

Compare Allegra ODT with other medications

• Hay Fever
• Urticaria

Lincomix

Dosage Form: FOR ANIMAL USE ONLY
Lincomix®

Soluble Powder

lincomycin hydrochloride

(agricultural grade) soluble powder

Antibacterial

SWINE: Directions for Use

Indications and Usage for Lincomix

Lincomix Soluble Powder is indicated for the treatment of swine dysentery (bloody scours).

Lincomix Dosage and Administration

Dosage

Administer at a dose rate of 250 mg of lincomycin per gallon of drinking water. In clinical studies, this dose rate provided an average of 3.8 mg of lincomycin per pound of body weight per day.

Treatment Period

The drug should be administered for a minimum of 5 consecutive days beyond the disappearance of symptoms (bloody stools) up to a maximum of 10 consecutive days. If water treatment is discontinued prior to this time, a lincomycin treatment program may be continued with lincomycin premix at 100 grams lincomycin per ton of complete feed as the sole ration according to label directions.

Administration

This bottle will medicate 768 gallons of drinking water providing 250 mg/gallon. A dose of 3.8 mg lincomycin per pound of body weight may be maintained by medicating the drinking water at a concentration of 250 mg per gallon of drinking water when pigs are consuming 1.5 gallons per 100 lbs of body weight per day. Under these circumstances the concentration of lincomycin required in medicated water may be adjusted to compensate for variations in age and weight of animals, the nature and severity of disease symptoms, environmental temperature and humidity, each of which affects water consumption.

For use in automatic water proportioners, prepare the stock solution by dissolving one bottle in six gallons of water: then adjust the proportioner to deliver 1 ounce of stock solution per gallon of drinking water.

NOTE: After a treatment program is discontinued, a control program for swine dysentery may be followed by feeding lincomycin premix at 40 grams lincomycin per ton of complete feed as the sole ration.

BROILER CHICKENS: Directions for Use

Indications and Usage for Lincomix

Lincomix Soluble Powder is indicated for the control of necrotic enteritis caused by Clostridium perfringens susceptible to lincomycin.

Lincomix Dosage and Administration

Dosage

Administer at a dose rate of 64 mg of lincomycin per gallon of drinking water.

Treatment Period

Start medication as soon as the diagnosis of necrotic enteritis is determined. If improvement is not noted within 24 to 48 hours, consult a licensed veterinarian or veterinary diagnostic laboratory to determine diagnosis. The drug should be administered for 7 consecutive days.

Administration

This bottle will medicate 3000 gallons of drinking water providing 64 mg/gallon.

NOTE: After water medication is discontinued, a control program for necrotic enteritis may be followed by feeding lincomycin premix at 2 grams lincomycin per ton of complete feed.

Precautions

1. Discard medicated drinking water if not used within 2 days. Fresh stock solution should be prepared daily. 2. If clinical signs of bloody scours (watery, mucoid or bloody stools) have not improved during the first 6 days of medication, discontinue treatment and redetermine the diagnosis. 3. Occasionally, swine fed lincomycin may within the first two days after the onset of treatment develop diarrhea and/or swelling of the anus. On rare occasions, some pigs may show reddening of the skin and irritable behavior. These conditions have been self-correcting within five to eight days without discontinuing the lincomycin treatment. 4. The safety of lincomycin has not been demonstrated for pregnant swine or swine intended for breeding. 5. Do not allow rabbits, hamsters, guinea pigs, horses, or ruminants access to water containing lincomycin. Ingestion by these species may result in severe gastrointestinal effects. 6. Do not use the water treatment and the feed treatment simultaneously. 7. Not for use in layer and breeder chickens.

Warnings

1. No drug withdrawal period is required before slaughter of swine receiving Lincomix Soluble Powder at the approved level of 250 mg per gallon of drinking water, nor before slaughter of birds receiving Lincomix Soluble Powder at the approved level of 64 mg per gallon of drinking water.


2. Not for human use.

Store at Controlled Room Temperature 20° to 25° C (68 ° to 77° F).

Restricted Drug (California)-Use Only as Directed

Made in China

Dist. by: Pharmacia & Upjohn Co., Div. of Pfizer Inc, New York, NY 10017

1453000

A73168-1

PRINCIPAL DISPLAY PANEL - 480 gram Bottle

Lincomix®

Soluble Powder

lincomycin hydrochloride

(agricultural grade) soluble powder

Antibacterial

FOR ORAL USE IN SWINE AND

BROILER CHICKENS ONLY

This bottle cotains as active ingredient:

Lincomycin hydrochloride,

equivalent to lincomycin . . . . 192 grams

NADA #111-636, Approved by FDA

Pfizer

PEEL FROM THE RIGHT

FOR SPANISH LANGUAGE

TAKE TIME

OBSERVE LABEL

DIRECTIONS

NET WT. 16.92 OZ

(480 GRAMS)

Lincomix  lincomycin hydrochloride  powder, for solution

Product Information Product Type OTC ANIMAL DRUG NDC Product Code (Source) 0009-0962 Route of Administration ORAL DEA Schedule

Active Ingredient/Active Moiety Ingredient Name Basis of Strength Strength LINCOMYCIN HYDROCHLORIDE (Lincomycin) Lincomycin 64 g  in 160 g

Inactive Ingredients Ingredient Name Strength No Inactive Ingredients Found

Product Characteristics Color      Score      Shape Size Flavor Imprint Code Contains

Packaging # NDC Package Description Multilevel Packaging 1 0009-0962-35 160 g In 1 BOTTLE, PLASTIC None 2 0009-0962-36 480 g In 1 BOTTLE, PLASTIC None

Marketing Information
Marketing Category	Application Number or Monograph Citation	Marketing Start Date	Marketing End Date
NADA	NADA111636	01/28/1983

Labeler - Pharmacia and Upjohn Company (829076566)

Establishment
Name	Address	ID/FEI	Operations
Pharmacia and Upjohn Company		829076566	API MANUFACTURE, MANUFACTURE

Establishment
Name	Address	ID/FEI	Operations
Pfizer Suzhou Animal Health Products Company Ltd		546995361	MANUFACTURE

Revised: 11/2009Pharmacia and Upjohn Company

Sertaconazole

Pronunciation: SIR-tuh-CON-ah-zole
Generic Name: Sertaconazole
Brand Name: Ertaczo

Sertaconazole is used for:

Treating athlete's foot infection that occurs between the toes in patients with a healthy immune system. Sertaconazole may also be used for other conditions as determined by your doctor.

Sertaconazole is an imidazole antifungal. It works by blocking the formation of the fungal cell wall, which results in the death of the fungus.

Do NOT use Sertaconazole if:

• you are allergic to any ingredient in Sertaconazole or to other imidazoles (eg, ketoconazole)


• you have a weakened immune system


• the skin in the area to be treated is irritated for other reasons

Contact your doctor or health care provider right away if any of these apply to you.

Before using Sertaconazole:

Some medical conditions may interact with Sertaconazole. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances

Some MEDICINES MAY INTERACT with Sertaconazole. Because little, if any, of Sertaconazole is absorbed into the blood, the risk of it interacting with another medicine is low.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Sertaconazole may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Sertaconazole:

Use Sertaconazole as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Clean and dry the affected area before applying the medicine.


• Gently rub the medicine until it is evenly distributed to the affected area and to a small section of healthy skin that surrounds the area.


• Do not bandage or wrap the affected area unless directed otherwise by your doctor.


• Wash your hands immediately after using Sertaconazole.


• Sertaconazole is for use on the skin only. Avoid getting Sertaconazole in your eyes, nose, vagina, or mouth.


• To clear up your infection completely, continue using Sertaconazole for the full course of treatment even if you feel better in a few days. Do not miss any doses.


• If you miss a dose of Sertaconazole, use it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not use 2 doses at once.

Ask your health care provider any questions you may have about how to use Sertaconazole.

Important safety information:

• If your condition does not improve in 2 weeks or if it becomes worse, contact your doctor for instructions.


• Overuse of topical products may worsen your condition.


• Do not use Sertaconazole for any condition other than the one for which it was prescribed.


• Sertaconazole is not recommended for use in CHILDREN younger than 12 years of age. Safety and effectiveness in this age group have not been confirmed.


• PREGNANCY and BREAST-FEEDING: If you plan on becoming pregnant, discuss with your doctor the benefits and risks of using Sertaconazole during pregnancy. It is unknown if Sertaconazole is excreted in breast milk. If you are or will be breast-feeding while you are using Sertaconazole, check with your doctor or pharmacist to discuss the risks to your baby.

Possible side effects of Sertaconazole:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Dry skin; skin tenderness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blistering, irritation, oozing, peeling, redness, scaling, shedding, or swelling of the affected area; darkening of the skin.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Sertaconazole side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately.

Proper storage of Sertaconazole:

Store Sertaconazole at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Keep Sertaconazole out of the reach of children and away from pets.

General information:

• If you have any questions about Sertaconazole, please talk with your doctor, pharmacist, or other health care provider.


• Sertaconazole is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Sertaconazole. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Sertaconazole resources

• Sertaconazole Side Effects (in more detail)
• Sertaconazole Use in Pregnancy & Breastfeeding
• Sertaconazole Support Group
• 0 Reviews for Sertaconazole - Add your own review/rating

Compare Sertaconazole with other medications

• Tinea Pedis

Alphaderm 1% & 10% w / w Cream

1. Name Of The Medicinal Product

Alphaderm 1% & 10%w/w Cream

2. Qualitative And Quantitative Composition

Alphaderm cream contains the active ingredients Hydrocortisone, PhEur 1% w/w and Urea, BP 10% w/w.

3. Pharmaceutical Form

Translucent white cream.

4. Clinical Particulars

4.1 Therapeutic Indications

For the treatment of all dry ichthyotic, eczematous conditions of the skin, including atopic, infantile, chronic allergic and irritant eczema, asteatotic, hyperkeratotic and lichenified eczema, neurodermatitis and prurigo.

4.2 Posology And Method Of Administration

Adults, children and the elderly. A small amount should be applied topically to the preferably dry affected areas twice daily. In resistant lesions occlusive dressings may be used but this is usually unnecessary because of the self occlusive nature of the special base.

4.3 Contraindications

Primary bacterial, viral and fungal diseases of the skin and secondarily infected eczemas or intertrigo acne, perioral dermatitis, rosacea and, in general, should not be used on weeping surfaces.

Known hypersensitivity to the active ingredients or any of its excipients.

4.4 Special Warnings And Precautions For Use

Caution should be exercised when using in children. In infants and children, long term continuous therapy should be avoided, as adrenal suppression can occur even without occlusion. Excessive absorption may occur when applied under napkins. Where possible treatment in infants should be limited to 5-7 days.

Application to moist or fissured skin may cause temporary irritation.

As with corticosteroids in general, prolonged application to the face and eyelids is undesirable and the cream should be kept away from the eyes.

4.5 Interaction With Other Medicinal Products And Other Forms Of Interaction

None known.

4.6 Pregnancy And Lactation

There is inadequate evidence for safety in human pregnancy. Topical administration of corticosteroids to pregnant animals can cause abnormalities of foetal development including cleft palate and intra-uterine growth retardation. There may, therefore, be a very small risk of such effects in the human foetus.

4.7 Effects On Ability To Drive And Use Machines

Alphaderm does not interfere with the ability to drive or use machines.

4.8 Undesirable Effects

If used correctly Alphaderm is unlikely to cause side effects. However, the following events have been observed with topical steroids, and although are rare with hydrocortisone, may occur, especially with long-term use; spread and worsening of untreated infection; thinning of the skin; irreversible striae atrophicae and telangiectasia; contact dermatitis, perioral dermatitis; acne; mild depigmentation which may be reversible. Atrophic changes may occur in intertriginous areas or nappy areas in young children.

4.9 Overdose

Chronically, grossly excessive over-use on large areas of skin in, for example, children could result in adrenal suppression of the hypothalamic-pituitary axis (HPA) as well as topical and systemic signs and symptoms of high corticosteroid dosage. In such cases, treatment should not stop abruptly. Adrenal insufficiency may require treatment with systemic hydrocortisone. Ingestion of a large amount of Alphaderm would be expected to result in gastrointestinal irritation, nausea, and possibly vomiting. Symptomatic and supportive care should be given. Liberal oral administration of milk or water may be helpful.

5. Pharmacological Properties

5.1 Pharmacodynamic Properties

Hydrocortisone is a naturally occurring glucocorticoid with proven anti-inflammatory and vasoconstrictive properties. Urea has been demonstrated to have hydrating, keratolytic and anti-pruritic properties. As such, urea has additional therapeutic effect in dry hyperkeratotic skin conditions. Alphaderm cream contains hydrocortisone and urea in a specially formulated base which assists the percutaneous transportation of the active ingredients to the site of action. Due to this formulation, Alphaderm acts as a moderately potent topical corticosteroid. The base is self-occlusive and fulfils the functions of both an ointment and a cream.

5.2 Pharmacokinetic Properties

Therapeutic activity of hydrocortisone depends upon the adequate penetration through the horny layer of the skin. The urea in the formulation solubilises part of the hydrocortisone and has a keratolytic effect. Both these factors increase penetration of the hydrocortisone

5.3 Preclinical Safety Data

None stated

6. Pharmaceutical Particulars

6.1 List Of Excipients

White soft paraffin, maize starch, isopropyl myristate, sycrowax HR-C, palmitic acid, sorbitan laurate and Arlatone G.

6.2 Incompatibilities

None known.

6.3 Shelf Life

Two years

6.4 Special Precautions For Storage

Do not store above 25°C.

6.5 Nature And Contents Of Container

Supplied in tubes of 30g and 100g.

6.6 Special Precautions For Disposal And Other Handling

A patient leaflet is provided with details of use and handling of the product.

7. Marketing Authorisation Holder

Alliance Pharmaceuticals Ltd

Avonbridge House

Bath Road

Chippenham

Wiltshire

SN15 2BB

8. Marketing Authorisation Number(S)

PL 16853/0060.

9. Date Of First Authorisation/Renewal Of The Authorisation

13 February 1990

10. Date Of Revision Of The Text

1^st February 2010

11. LEGAL STATUS

POM