Lortuss LQ Liquid

Pronunciation: dox-IL-a-meen/SOO-doe-e-FED-rin
Generic Name: Doxylamine/Pseudoephedrine
Brand Name: Lortuss LQ

Lortuss LQ Liquid is used for:

Relieving symptoms of sinus congestion, runny nose, itching of the nose and throat, itchy or watery eyes, and sneezing due to colds, hay fever, and allergies. It may also be used for other conditions as determined by your doctor.

Lortuss LQ Liquid is an antihistamine and decongestant combination. The antihistamine works by blocking the action of histamine and reducing symptoms such as watery eyes and sneezing. The decongestant relieves nasal congestion by causing vasoconstriction and shrinkage of the nasal mucous membranes and promoting drainage.

Do NOT use Lortuss LQ Liquid if:

• you are allergic to any ingredient in Lortuss LQ Liquid


• you have severe high blood pressure, severe heart blood vessel disease, rapid heartbeat, or severe heart problems


• you are unable to urinate or are having an asthma attack


• you use any product containing diphenhydramine


• you take droxidopa, sodium oxybate (GHB), or if you have taken furazolidone or a monoamine oxidase inhibitor (MAOI) (eg, phenelzine) within the last 14 days

Contact your doctor or health care provider right away if any of these apply to you.

Before using Lortuss LQ Liquid:

Some medical conditions may interact with Lortuss LQ Liquid. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have a history of adrenal gland problems (eg, adrenal gland tumor), heart problems (eg, cor pulmonale; fast, slow, or irregular heartbeat; heart disease), high blood pressure, diabetes, blood vessel problems, a stroke, glaucoma or increased pressure in the eye, seizures, or thyroid problems


• if you have a history of asthma or other breathing problems, chronic cough, lung problems (eg, chronic bronchitis, emphysema), chronic obstructive pulmonary disease (COPD), or sleep apnea


• if you have a blockage of your bladder, stomach, or bowels; ulcers; trouble sleeping; an enlarged prostate or other prostate problems; or trouble urinating

Some MEDICINES MAY INTERACT with Lortuss LQ Liquid. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Digoxin or droxidopa because the risk of irregular heartbeat or a heart attack may be increased


• Beta-blockers (eg, propranolol), furazolidone, linezolid, MAOIs (eg, phenelzine), sodium oxybate (GHB), tricyclic antidepressants (eg, amitriptyline), or urinary alkalinizers (eg, sodium bicarbonate) because they may increase the risk of Lortuss LQ Liquid's side effects


• Bromocriptine or hydantoins (eg, phenytoin) because the risk of their side effects may be increased by Lortuss LQ Liquid


• Guanadrel, guanethidine, mecamylamine, methyldopa, or reserpine because their effectiveness may be decreased by Lortuss LQ Liquid

This may not be a complete list of all interactions that may occur. Ask your health care provider if Lortuss LQ Liquid may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Lortuss LQ Liquid:

Use Lortuss LQ Liquid as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Lortuss LQ Liquid may be taken with or without food. If stomach upset occurs, take with food to reduce stomach irritation.


• Use a measuring device marked for medicine dosing. Ask your pharmacist for help if you are unsure of how to measure your dose.


• If you miss a dose of Lortuss LQ Liquid and you are taking it regularly, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Lortuss LQ Liquid.

Important safety information:

• Lortuss LQ Liquid may cause drowsiness, dizziness, or blurred vision. These effects may be worse if you take it with alcohol or certain medicines. Use Lortuss LQ Liquid with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.


• Check with your doctor before you use medicines that may cause drowsiness (eg, sleep aids, muscle relaxers) while you are using Lortuss LQ Liquid; it may add to their effects. Ask your pharmacist if you have questions about which medicines may cause drowsiness.


• Do not drink alcohol while you are using Lortuss LQ Liquid.


• If you have trouble sleeping, ask your pharmacist or doctor about the best time of day to take Lortuss LQ Liquid.


• Do not take diet or appetite control medicines while you are taking Lortuss LQ Liquid without checking with your doctor.


• Lortuss LQ Liquid has a decongestant and an antihistamine in it. Before you start any new medicine, check the label to see if it has a decongestant or antihistamine in it too. If it does or if you are not sure, check with your doctor or pharmacist.


• Do NOT take more than the recommended dose or use for longer than prescribed without checking with your doctor.


• If your symptoms do not get better within 7 days; if they get worse; if they occur along with a fever, rash, or persistent headache; or if new symptoms occur, check with your doctor.


• Lortuss LQ Liquid may cause you to become sunburned more easily. Avoid the sun, sunlamps, or tanning booths until you know how you react to Lortuss LQ Liquid. Use a sunscreen or wear protective clothing if you must be outside for more than a short time.


• Lortuss LQ Liquid may interfere with skin allergy tests. If you are scheduled for a skin test, talk to your doctor. You may need to stop taking Lortuss LQ Liquid for a few days before the tests.


• Tell your doctor or dentist that you take Lortuss LQ Liquid before you receive any medical or dental care, emergency care, or surgery.


• Use Lortuss LQ Liquid with caution in the ELDERLY; they may be more sensitive to its effects, especially confusion, dizziness, drowsiness, dry mouth, excitability, low blood pressure, and trouble urinating.


• Caution is advised when using Lortuss LQ Liquid in CHILDREN; they may be more sensitive to its effects, especially excitability.


• Lortuss LQ Liquid should not be used in CHILDREN younger than 6 years; safety and effectiveness in these children have not been confirmed.


• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of taking Lortuss LQ Liquid while you are pregnant. It is not known if Lortuss LQ Liquid is found in breast milk. Do not breast-feed while taking Lortuss LQ Liquid.

Possible side effects of Lortuss LQ Liquid:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; diarrhea; dizziness; drowsiness; dry mouth, nose, or throat; excitability; headache; loss of appetite; nausea; nervousness or anxiety; trouble sleeping; upset stomach; vomiting; weakness.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); blurred vision or other vision changes; confusion; difficulty urinating or inability to urinate; fast or irregular heartbeat; fever, chills, or persistent sore throat; hallucinations; mood or mental changes; persistent trouble sleeping; restlessness; seizures; severe dizziness, drowsiness, lightheadedness, or headache; tremor.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Lortuss LQ side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include blurred vision; confusion; hallucinations; ringing in the ears; seizures; severe dizziness, lightheadedness, or headache; severe drowsiness; unusually fast, slow, or irregular breathing; unusually fast, slow, or irregular heartbeat; vomiting.

Proper storage of Lortuss LQ Liquid:

Store Lortuss LQ Liquid at room temperature, between 59 and 86 degrees F (15 and 30 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Lortuss LQ Liquid out of the reach of children and away from pets.

General information:

• If you have any questions about Lortuss LQ Liquid, please talk with your doctor, pharmacist, or other health care provider.


• Lortuss LQ Liquid is to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Lortuss LQ Liquid. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Lortuss LQ resources

• Lortuss LQ Side Effects (in more detail)
• Lortuss LQ Use in Pregnancy & Breastfeeding
• Lortuss LQ Drug Interactions
• 0 Reviews for Lortuss LQ - Add your own review/rating

Compare Lortuss LQ with other medications

• Cough and Nasal Congestion

Fe Caps Controlled-Release Capsules

Pronunciation: FER-us SUL-fate
Generic Name: Ferrous Sulfate
Brand Name: Examples include Fe Caps and Slow Fe

Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children younger than 6 years old. Keep this product out of the reach of children. In case of an accidental overdose, call a doctor or poison control center right away.

Fe Caps Controlled-Release Capsules are used for:

Preventing or treating low levels of iron in the blood. It may also be used for other conditions as determined by your doctor.

Fe Caps Controlled-Release Capsules are an essential body mineral. It works by replacing iron in your body if your body does not produce enough on its own.

Do NOT use Fe Caps Controlled-Release Capsules if:

• you are allergic to any ingredient in Fe Caps Controlled-Release Capsules


• you have high levels of iron in your blood

Contact your doctor or health care provider right away if any of these apply to you.

Before using Fe Caps Controlled-Release Capsules:

Some medical conditions may interact with Fe Caps Controlled-Release Capsules. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

• if you are pregnant, planning to become pregnant, or are breast-feeding


• if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement


• if you have allergies to medicines, foods, or other substances


• if you have inflammation of the intestines, Crohn disease, digestive problems, ulcers, anemia, or a blood disease (eg, porphyria, thalassemia)


• if you have had multiple blood transfusions

Some MEDICINES MAY INTERACT with Fe Caps Controlled-Release Capsules. Tell your health care provider if you are taking any other medicines, especially any of the following:

• Doxycycline, mycophenolate, penicillamine, or thyroid hormones (eg, levothyroxine) because their effectiveness may be decreased by Fe Caps Controlled-Release Capsules

This may not be a complete list of all interactions that may occur. Ask your health care provider if Fe Caps Controlled-Release Capsules may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

How to use Fe Caps Controlled-Release Capsules:

Use Fe Caps Controlled-Release Capsules as directed by your doctor. Check the label on the medicine for exact dosing instructions.

• Take Fe Caps Controlled-Release Capsules by mouth with or without food. If stomach upset occurs, take with food to reduce stomach irritation.


• Swallow Fe Caps Controlled-Release Capsules whole. Do not break, crush, or chew before swallowing.


• Take Fe Caps Controlled-Release Capsules with a full glass of water (8 oz/240 mL). Do not lie down for 30 minutes after taking Fe Caps Controlled-Release Capsules.


• If you are also taking an antacid, a bisphosphonate (eg, alendronate), a cephalosporin (eg, cephalexin), methyldopa, penicillamine, a quinolone (eg, ciprofloxacin), or a tetracycline (eg, minocycline) along with Fe Caps Controlled-Release Capsules, you may need to space the doses several hours apart. Ask your doctor or pharmacist how much time is needed between doses of Fe Caps Controlled-Release Capsules and your other medicines.


• Certain foods and drinks may decrease the amount of Fe Caps Controlled-Release Capsules that works in your body. Ask your doctor or pharmacist how you should take Fe Caps Controlled-Release Capsules if you consume whole grain breads or cereal, dairy products, coffee, or tea.


• If you miss a dose of Fe Caps Controlled-Release Capsules, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Fe Caps Controlled-Release Capsules.

Important safety information:

• Do not take large doses of vitamins while you use Fe Caps Controlled-Release Capsules unless your doctor tells you to.


• Do NOT take more than the recommended dose or take for longer than 6 months without checking with your doctor.


• Fe Caps Controlled-Release Capsules has iron in it. Iron overdose is a leading cause of fatal poisoning in children younger than 6 years old. In case of an overdose, call a doctor or poison control center right away.


• Lab tests, including complete blood cell counts and blood iron levels, may be performed while you use Fe Caps Controlled-Release Capsules. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.


• Fe Caps Controlled-Release Capsules should be used with extreme caution in CHILDREN; safety and effectiveness in children have not been confirmed.


• PREGNANCY and BREAST-FEEDING: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Fe Caps Controlled-Release Capsules while you are pregnant. Fe Caps Controlled-Release Capsules are found in breast milk. If you are or will be breast-feeding while you use Fe Caps Controlled-Release Capsules, check with your doctor. Discuss any possible risks to your baby.

Possible side effects of Fe Caps Controlled-Release Capsules:

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Constipation; darkened or green stools; diarrhea; nausea; stomach upset.

Seek medical attention right away if any of these SEVERE side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); black, tarry stools; blood or streaks of blood in the stool; fever; vomiting with continuing sharp stomach pain.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider. Call your doctor for medical advice about side effects. To report side effects to the appropriate agency, please read the Guide to Reporting Problems to FDA.

See also: Fe Caps side effects (in more detail)

If OVERDOSE is suspected:

Contact 1-800-222-1222 (the American Association of Poison Control Centers), your local poison control center, or emergency room immediately. Symptoms may include difficulty breathing; loss of consciousness; seizures; severe nausea; stomach pain; tarry stools; unusual tiredness; vomiting; weak, fast heartbeat.

Proper storage of Fe Caps Controlled-Release Capsules:

Store Fe Caps Controlled-Release Capsules at room temperature, between 68 and 77 degrees F (20 and 25 degrees C). Store away from heat, moisture, and light. Do not store in the bathroom. Keep Fe Caps Controlled-Release Capsules out of the reach of children and away from pets.

General information:

• If you have any questions about Fe Caps Controlled-Release Capsules, please talk with your doctor, pharmacist, or other health care provider.


• Fe Caps Controlled-Release Capsules are to be used only by the patient for whom it is prescribed. Do not share it with other people.


• If your symptoms do not improve or if they become worse, check with your doctor.


• Check with your pharmacist about how to dispose of unused medicine.

This information is a summary only. It does not contain all information about Fe Caps Controlled-Release Capsules. If you have questions about the medicine you are taking or would like more information, check with your doctor, pharmacist, or other health care provider.

Issue Date: February 1, 2012

Database Edition 12.1.1.002

Copyright © 2012 Wolters Kluwer Health, Inc.

More Fe Caps resources

• Fe Caps Side Effects (in more detail)
• Fe Caps Use in Pregnancy & Breastfeeding
• Fe Caps Drug Interactions
• Fe Caps Support Group
• 0 Reviews for Fe Caps - Add your own review/rating

Compare Fe Caps with other medications

• Anemia Associated with Chronic Renal Failure
• Iron Deficiency Anemia
• Vitamin/Mineral Supplementation and Deficiency
• Vitamin/Mineral Supplementation during Pregnancy/Lactation

Vanatrip

Generic Name: amitriptyline (a mee TRIP ti leen)

Brand Names: Vanatrip

What is Vanatrip (amitriptyline)?

Amitriptyline is a tricyclic antidepressant. Amitriptyline affects chemicals in the brain that may become unbalanced.

Amitriptyline is used to treat symptoms of depression.

Amitriptyline may also be used for purposes not listed in this medication guide.

What is the most important information I should know about Vanatrip (amitriptyline)?

Do not use this medication if you are allergic to amitriptyline, or if you have recently had a heart attack. Do not use amitriptyline if you have used an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) within the past 14 days.

You may have thoughts about suicide when you first start taking an antidepressant, especially if you are younger than 24 years old. Your doctor will need to check you at regular visits for at least the first 12 weeks of treatment.

Video: Treatment for Depression

Treatments for depression are getting better everyday and there are things you can start doing right away.

Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.

What should I discuss with my healthcare provider before taking Vanatrip (amitriptyline)?

You should not use this medication if you are allergic to amitriptyline, or if you have recently had a heart attack. Do not use amitriptyline if you have used an MAO inhibitor such as furazolidone (Furoxone), isocarboxazid (Marplan), phenelzine (Nardil), rasagiline (Azilect), selegiline (Eldepryl, Emsam, Zelapar), or tranylcypromine (Parnate) in the last 14 days. A dangerous drug interaction could occur, leading to serious side effects.

To make sure you can safely take amitriptyline, tell your doctor if you have any of these other conditions:

• 
  

  heart disease;

  
  


• 
  

  a history of heart attack, stroke, or seizures;

  
  


• 
  

  bipolar disorder (manic-depression);

  
  


• 
  

  schizophrenia or other mental illness;

  
  


• 
  

  diabetes (amitriptyline may raise or lower blood sugar);

  
  


• 
  

  overactive thyroid;

  
  


• 
  

  glaucoma; or

  
  


• 
  

  problems with urination.

  
  

You may have thoughts about suicide while taking an antidepressant, especially if you are younger than 24 years old. Tell your doctor if you have worsening depression or suicidal thoughts during the first several weeks of treatment, or whenever your dose is changed.

Your family or other caregivers should also be alert to changes in your mood or symptoms. Your doctor will need to check you at regular visits for at least the first 12 weeks of treatment.

FDA pregnancy category C. It is not known whether amitriptyline will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. Amitriptyline can pass into breast milk and may harm a nursing baby. You should not breast-feed while you are using amitriptyline. Do not give this medication to anyone under 12 years old without medical advice.

How should I take Vanatrip (amitriptyline)?

Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

If you need surgery, tell the surgeon ahead of time that you are using amitriptyline. You may need to stop using the medicine for a short time. Do not stop using amitriptyline suddenly, or you could have unpleasant withdrawal symptoms. Ask your doctor how to avoid withdrawal symptoms when you stop using amitriptyline. It may take up to 4 weeks before your symptoms improve. Keep using the medication as directed and tell your doctor if your symptoms do not improve after 4 weeks of treatment. Store at room temperature away from moisture, heat, and light.

What happens if I miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. An overdose of amitriptyline can be fatal.

Overdose symptoms may include uneven heartbeats, extreme drowsiness, confusion, agitation, vomiting, hallucinations, feeling hot or cold, muscle stiffness, seizure (convulsions), or fainting.

What should I avoid while taking Vanatrip (amitriptyline)?

Do not drink alcohol. It can cause dangerous side effects when taken together with amitriptyline. This medication may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. Avoid exposure to sunlight or tanning beds. Amitriptyline can make you sunburn more easily. Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.

Vanatrip (amitriptyline) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, anxiety, panic attacks, trouble sleeping, or if you feel impulsive, irritable, agitated, hostile, aggressive, restless, hyperactive (mentally or physically), more depressed, or have thoughts about suicide or hurting yourself.

Call your doctor at once if you have a serious side effect such as:

• 
  

  chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling;

  
  


• 
  

  sudden numbness or weakness, especially on one side of the body;

  
  


• 
  

  sudden severe headache, confusion, problems with vision, speech, or balance;

  
  


• 
  

  pounding heartbeats or fluttering in your chest;

  
  


• 
  

  feeling like you might pass out;

  
  


• 
  

  confusion, hallucinations, seizures (convulsions);

  
  


• 
  

  restless muscle movements in your eyes, tongue, jaw, or neck, uncontrollable shaking or tremor;

  
  


• 
  

  extreme thirst with headache, nausea, vomiting, and weakness;

  
  


• 
  

  numbness, burning pain, or tingly feeling;

  
  


• 
  

  easy bruising, unusual bleeding (nose, mouth, vagina, or rectum), purple or red pinpoint spots under your skin;

  
  


• 
  

  skin rash, bruising, severe tingling, numbness, pain, muscle weakness;

  
  


• 
  

  urinating less than usual or not at all.

  
  

Less serious side effects may include:

• 
  

  nausea, vomiting, constipation, diarrhea, loss of appetite;

  
  


• 
  

  dry mouth, unpleasant taste;

  
  


• 
  

  feeling dizzy, drowsy, or tired;

  
  


• 
  

  trouble concentrating;

  
  


• 
  

  nightmares;

  
  


• 
  

  blurred vision, headache, ringing in your ears;

  
  


• 
  

  breast swelling (in men or women); or

  
  


• 
  

  decreased sex drive, impotence, or difficulty having an orgasm.

  
  

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Vanatrip (amitriptyline)?

Cold or allergy medicine, sedatives, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures or anxiety can add to sleepiness caused by amitriptyline. Tell your doctor if you regularly use any of these medicines, or any other antidepressants.

Before taking amitriptyline, tell your doctor if you have used an "SSRI" antidepressant in the past 5 weeks, such as citalopram (Celexa), escitalopram (Lexapro), fluoxetine (Prozac, Sarafem, Symbyax), fluvoxamine (Luvox), paroxetine (Paxil), or sertraline (Zoloft).

Tell your doctor about all other medicines you use, especially:

• 
  

  cimetidine (Tagamet);

  
  


• 
  

  isoniazid (for treating tuberculosis);

  
  


• 
  

  methimazole (Tapazole);

  
  


• 
  

  nicardipine (Cardene);

  
  


• 
  

  ropinirole (Requip);

  
  


• 
  

  ticlopidine (Ticlid);

  
  


• 
  

  an antibiotic such as terbinafine (Lamisil);

  
  


• 
  

  anti-malaria medication such as chloroquine (Arelan) or pyrimethamine (Daraprim), or quinine (Qualaquin);

  
  


• 
  

  HIV or AIDS medicine such as delavirdine (Rescriptor) or ritonavir (Norvir, Kaletra);

  
  


• 
  

  medicine to treat psychiatric disorders, such as aripiprazole (Abilify), chlorpromazine (Thorazine), clozapine (Clozaril, FazaClo), fluphenazine (Permitil, Prolixin), haloperidol (Haldol), perphenazine (Trilafon), or thioridazine (Mellaril);

  
  


• 
  

  a heart rhythm medication such as amiodarone (Cordarone, Pacerone), dofetilide (Tikosyn), ibutilide (Corvert), or sotalol (Betapace); or

  
  


• 
  

  a heart rhythm medication such as disopyramide (Norpace), dronedarone (Multaq), flecainide (Tambocor), mexiletine (Mexitil), procainamide (Pronestyl), propafenone (Rythmol), or quinidine (Quin-G).

  
  

This list is not complete and there are many other drugs that can interact with amitriptyline. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor. Keep a list of all your medicines and show it to any healthcare provider who treats you.

More Vanatrip resources

• Vanatrip Side Effects (in more detail)
• Vanatrip Use in Pregnancy & Breastfeeding
• Vanatrip Drug Interactions
• Vanatrip Support Group
• 1 Review for Vanatrip - Add your own review/rating

• Vanatrip Advanced Consumer (Micromedex) - Includes Dosage Information


• Amitriptyline Prescribing Information (FDA)


• Amitriptyline MedFacts Consumer Leaflet (Wolters Kluwer)


• Amitriptyline Hydrochloride Monograph (AHFS DI)


• Elavil Consumer Overview

Compare Vanatrip with other medications

• Anxiety and Stress
• Burning Mouth Syndrome
• Cyclic Vomiting Syndrome
• Depression
• Dysautonomia
• Dysthymia
• Fibromyalgia
• Hyperhidrosis
• Insomnia
• Interstitial Cystitis
• Migraine Prevention
• Neurotic Depression
• Pain
• Post Traumatic Stress Disorder
• Reflex Sympathetic Dystrophy Syndrome
• Somatoform Pain Disorder
• Urinary Incontinence
• Vulvodynia

Where can I get more information?

• Your pharmacist can provide more information about amitriptyline.

See also: Vanatrip side effects (in more detail)

Complete-RF Prenatal

Dosage Form: tablet, film coated
Complete-RF Prenatal

Prenatal Multivitamin & Multimineral Tablets

Rx Only

Complete-RF Prenatal Description

Complete-RF Prenatal Tablets are oval, dye free, white, film-coated, oil and water soluble multivitamin/multimineral tablets debossed "T008" on one side.

Each tablet for oral administration contains:
Vitamin C (ascorbic acid)	120 mg
Vitamin D3 (cholecalciferol)	400 IU
Vitamin E (dl-alpha tocopheryl acetate)	30 IU
Vitamin B1 (thiamine mononitrate)	3 mg
Vitamin B2 (riboflavin)	3.4 mg
Niacin (niacinamide)	20 mg
Vitamin B6 (pyridoxine hydrochloride)	20 mg
Folic Acid	1 mg
Vitamin B12 (cyanocobalamin)	12 mcg
Calcium (calcium carbonate)	200 mg
Elemental Iron (carbonyl iron)	90 mg
Magnesium (magnesium oxide)	30 mg
Zinc (zinc oxide)	25 mg
Copper (cupric oxide)	2 mg
Docusate Sodium	50 mg

Inactive Ingredients

Citric Acid, Croscarmellose Sodium, Fumed Silica, Gum Arabic, Magnesium Stearate, Microcrystalline Cellulose, PVP K30, Stearic Acid, TriPotassium Citrate.

Indications and Usage for Complete-RF Prenatal

Complete-RF Prenatal is a multivitamin/multimineral nutritional supplement indicated for use in improving the nutritional status of women throughout pregnancy and in the postnatal period for both lactating and nonlactating mothers. Complete-RF Prenatal can also be beneficial in improving the nutritional status of women prior to conception.

Contraindications

This product is contraindicated in patients with a known hypersensitivity to any of the ingredients.

Warnings

Folic acid alone is improper therapy in the treatment of pernicious anemia and other megaloblastic anemias where vitamin B12 is deficient. Folic acid in doses above 1.0 mg daily may obscure pernicious anemia in that hematologic remission can occur while neurological manifestations remain progressive.

WARNING

Accidental overdose of iron-containing products is a leading cause of fatal poisoning in children under 6. KEEP THIS PRODUCT OUT OF REACH OF CHILDREN. In case of accidental overdose, call a doctor or poison control center immediately.

Precautions

Pediatric Use

Safety and effectiveness in pediatric patients have not been established.

Geriatric Use

Clinical studies on this product have not been performed in sufficient numbers of subjects aged 65 and over to determine whether elderly subjects respond differently from younger subjects. In general, dose selection for an elderly patient should be cautious, usually starting at the low end of the dosing range, reflecting the greater frequency of decreased hepatic, renal, or cardiac functions, and of concomitant disease or other drug therapy.

Adverse Reactions

Adverse reactions with iron therapy may include constipation, diarrhea, nausea, vomiting, dark stools and abdominal pain. Adverse reactions with iron therapy are usually transient. Allergic sensitization has been reported following both oral and parenteral administration of folic acid.

Complete-RF Prenatal Dosage and Administration

One tablet daily or as prescribed by a physician.

How is Complete-RF Prenatal Supplied

Complete-RF Prenatal is supplied in bottles of 90 tablets.

NDC 13811-008-90

STORAGE

Store at Controlled Room Temperature 25°C (77°F); excursions permitted to 15°-30° C (59°- 86°F). [See USP]. Call your doctor about side effects. You may report side effects by calling 888 9 TRIGEN (888-987-4436). KEEP THIS AND ALL DRUGS OUT OF THE REACH OF CHILDREN.

Rx Only

All prescriptions using this product shall be pursuant to state statutes as applicable. This is not an Orange Book product. There are no implied or explicit claims on therapeutic equivalence.

Manufactured for:

TRIGEN Laboratories, Inc.

Sayreville, NJ 08872

www.trigenlab.com

MADE IN CANADA

Rev. 11/10

PRINCIPAL DISPLAY PANEL - 90 Tablet Bottle Label

Rx Only

NDC 13811-008-90

90 Tablets

Complete-RF

Prenatal

Prenatal Multivitamin/Multimineral Tablets

TRIGEN

LABORATORIES

Complete-RF Prenatal  ascorbic acid, cholecalciferol, .alpha.-tocopherol acetate, dl-, thiamine mononitrate, riboflavin, niacinamide, pyridoxine hydrochloride, folic acid, cyanocobalamin, calcium carbonate, iron, magnesium oxide, zinc oxide, cupric oxide, and docusate sodium  tablet, film coated

Product Information Product Type HUMAN PRESCRIPTION DRUG NDC Product Code (Source) 13811-008 Route of Administration ORAL DEA Schedule

Active Ingredient/Active Moiety Ingredient Name Basis of Strength Strength Ascorbic Acid (Ascorbic Acid) Ascorbic Acid 120 mg Cholecalciferol (Cholecalciferol) Cholecalciferol 400 [iU] .Alpha.-Tocopherol Acetate, DL- (.Alpha.-Tocopherol Acetate, DL-) .Alpha.-Tocopherol Acetate, DL- 30 [iU] Thiamine Mononitrate (Thiamine) Thiamine Mononitrate 3 mg Riboflavin (Riboflavin) Riboflavin 3.4 mg Niacinamide (Niacinamide) Niacinamide 20 mg Pyridoxine Hydrochloride (Pyridoxine) Pyridoxine Hydrochloride 20 mg Folic Acid (Folic Acid) Folic Acid 1 mg Cyanocobalamin (Cyanocobalamin) Cyanocobalamin 12 ug Calcium Carbonate (Calcium Cation) Calcium Carbonate 200 mg Iron (Iron) Iron 90 mg Magnesium Oxide (Magnesium Oxide) Magnesium Oxide 30 mg Zinc Oxide (Zinc Oxide) Zinc Oxide 25 mg Cupric Oxide (Cupric Oxide) Cupric Oxide 2 mg Docusate Sodium (Docusate) Docusate Sodium 50 mg

Inactive Ingredients Ingredient Name Strength Citric Acid Monohydrate   Croscarmellose Sodium   Silicon Dioxide   Acacia   Magnesium Stearate   Cellulose, Microcrystalline   Povidone K30   Stearic Acid   Potassium Citrate Anhydrous

Product Characteristics Color WHITE Score no score Shape OVAL Size 16mm Flavor Imprint Code T008 Contains

Packaging # NDC Package Description Multilevel Packaging 1 13811-008-90 90 TABLET In 1 BOTTLE None

Marketing Information
Marketing Category	Application Number or Monograph Citation	Marketing Start Date	Marketing End Date
Unapproved drug other		12/01/2010

Labeler - TRIGEN Laboratories, Inc. (830479668)

Revised: 09/2011TRIGEN Laboratories, Inc.

More Complete-RF Prenatal resources

• Complete-RF Prenatal Use in Pregnancy & Breastfeeding
• Drug Images
• Complete-RF Prenatal Drug Interactions
• Complete-RF Prenatal Support Group
• 21 Reviews for Complete-RF Prenatal - Add your own review/rating

Compare Complete-RF Prenatal with other medications

• Vitamin/Mineral Supplementation during Pregnancy/Lactation

Atuss HX

Generic Name: guaifenesin and hydrocodone (gwye FEN e sin and HYE droe KOE done)

Brand Names: A-Cof DH, Canges-XP, Codiclear DH, Condasin, Cotuss V, Execlear, Extendryl HC, Hycotuss Expectorant, Hydrocod-GF, Kwelcof, Monte-G HC, Narcof, Pancof XP, Pneumotussin 2.5, Relasin-HCX, Touro HC, Tussicle, Tusso-DF, Vi-Q-Tuss, Vitussin Expectorant, Xpect-HC, Z-Cof HCX

What is Atuss HX (guaifenesin and hydrocodone)?

Guaifenesin is an expectorant. It helps loosen congestion in your chest and throat, making it easier to cough out through your mouth.

Hydrocodone is a narcotic cough suppressant.

Guaifenesin and hydrocodone is used to treat cough and reduce chest congestion caused by the common cold, flu, or allergies.

Guaifenesin and hydrocodone may also be used for other purposes not listed in this medication guide.

What is the most important information I should know about Atuss HX (guaifenesin and hydrocodone)?

This medication can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Avoid drinking alcohol. It may increase drowsiness and dizziness caused by guaifenesin and hydrocodone. Tell your doctor if you regularly use other medicines that make you sleepy (such as other cold or allergy medicine, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to sleepiness caused by guaifenesin and hydrocodone. Hydrocodone may be habit-forming and should be used only by the person it was prescribed for. Hydrocodone should never be given to another person, especially someone who has a history of drug abuse or addiction. Keep the medication in a secure place where others cannot get to it.

What should I discuss with my healthcare provider before taking Atuss HX (guaifenesin and hydrocodone)?

Hydrocodone may be habit-forming and should be used only by the person it was prescribed for. Hydrocodone should never be shared with another person, especially someone who has a history of drug abuse or addiction. Keep the medication in a secure place where others cannot get to it. Do not use this medicine if you are allergic to hydrocodone or guaifenesin.

Before taking this medication, tell your doctor if you have:

• kidney disease;


• liver disease;


• 
  

  asthma;

  
  


• 
  

  urination problems;

  
  


• 
  

  an enlarged prostate;

  
  


• 
  

  a thyroid disorder;

  
  


• 
  

  seizures or epilepsy;

  
  


• 
  

  gallbladder disease;

  
  


• 
  

  a head injury; or

  
  


• 
  

  Addison's disease.

  
  

If you have any of these conditions, you may not be able to take guaifenesin and hydrocodone, or you may need a dose adjustment or special tests during treatment.

FDA pregnancy category C. This medication may be harmful to an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant during treatment. Guaifenesin and hydrocodone passes into breast milk and may be harmful to a nursing baby. Do not take guaifenesin and hydrocodone without telling your doctor if you are breast-feeding a baby.

How should I take Atuss HX (guaifenesin and hydrocodone)?

Take this medication exactly as prescribed by your doctor. Do not take it in larger amounts or for longer than recommended. Follow the directions on your prescription label.

Guaifenesin and hydrocodone can be taken with or without food.

Measure liquid medicine with a special dose-measuring spoon or cup, not a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist for one.

Do not take more of this medication or take it for longer than is recommended. Call your doctor if your symptoms do not improve, or if they get worse. Store guaifenesin and hydrocodone at room temperature away from moisture and heat. Keep track of how many pills have been used from each new bottle of this medicine. Hydrocodone is a drug of abuse and you should be aware if any person in the household is using this medicine improperly or without a prescription.

What happens if I miss a dose?

Take the missed dose as soon as you remember. If it is almost time for your next dose, wait until then to take the medicine and skip the missed dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention if you think you have used too much of this medicine.

Overdose symptoms may include extreme drowsiness, sweating, pinpoint pupils, nausea, vomiting, dry mouth, confusion, cold and clammy skin, muscle weakness, fainting, weak pulse, slow heart rate, seizure (convulsions), weak or shallow breathing, or breathing that stops.

What should I avoid while taking Atuss HX (guaifenesin and hydrocodone)?

This medication can cause side effects that may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be awake and alert. Avoid drinking alcohol. It may increase drowsiness and dizziness caused by guaifenesin and hydrocodone. Tell your doctor if you regularly use other medicines that make you sleepy (such as other cold or allergy medicine, narcotic pain medicine, sleeping pills, muscle relaxers, and medicine for seizures, depression, or anxiety). They can add to sleepiness caused by guaifenesin and hydrocodone.

Do not take other over-the-counter cough, cold, allergy, pain, or sleep medications without first asking your doctor or pharmacist. Guaifenesin is contained in many medicines available over the counter. If you take certain products together you may accidentally take too much guaifenesin. Read the label of any other medicine you are using to see if it contains guaifenesin.

Atuss HX (guaifenesin and hydrocodone) side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Stop using this medication and call your doctor at once if you have a serious side effect such as:

• 
  

  slow heart rate, weak or shallow breathing;

  
  


• 
  

  feeling like you might pass out;

  
  


• 
  

  confusion, fear, unusual thoughts or behavior;

  
  


• 
  

  seizure (convulsions); or

  
  


• 
  

  urinating less than usual or not at all.

  
  

Less serious side effects may include:

• 
  

  dizziness, drowsiness;

  
  


• 
  

  nausea, vomiting, upset stomach;

  
  


• 
  

  blurred vision;

  
  


• 
  

  constipation;

  
  


• 
  

  dry mouth; or

  
  


• 
  

  sweating.

  
  

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect Atuss HX (guaifenesin and hydrocodone)?

Before taking this medication, tell your doctor if you are using any of the following drugs:

• 
  

  antidepressants such as amitriptyline (Elavil, Etrafon), clomipramine (Anafranil), imipramine (Janimine, Tofranil), and others;

  
  


• 
  

  atropine (Donnatal, and others), benztropine (Cogentin), dimenhydrinate (Dramamine), glycopyrrolate (Robinul), mepenzolate (Cantil), methscopolamine (Pamine), or scopolamine (Transderm-Scop);

  
  


• 
  

  bladder or urinary medications such as darifenacin (Enablex), flavoxate (Urispas), oxybutynin (Ditropan, Oxytrol), tolterodine (Detrol), or solifenacin (Vesicare);

  
  


• 
  

  a bronchodilator such as ipratropium (Atrovent) or tiotropium (Spiriva); or

  
  


• 
  

  irritable bowel medications such as dicyclomine (Bentyl), hyoscyamine (Anaspaz, Cystospaz, Levsin, and others), or propantheline (Pro-Banthine).

  
  

This list is not complete and there may be other drugs that can interact with guaifenesin and hydrocodone. Tell your doctor about all the prescription and over-the-counter medications you use. This includes vitamins, minerals, herbal products, and drugs prescribed by other doctors. Do not start using a new medication without telling your doctor.

More Atuss HX resources

• Atuss HX Side Effects (in more detail)
• Atuss HX Use in Pregnancy & Breastfeeding
• Atuss HX Drug Interactions
• Atuss HX Support Group
• 0 Reviews for Atuss HX - Add your own review/rating

• CodiCLEAR DH Liquid MedFacts Consumer Leaflet (Wolters Kluwer)


• Entuss Liquid MedFacts Consumer Leaflet (Wolters Kluwer)


• Tusso-HC Sustained-Release Tablets MedFacts Consumer Leaflet (Wolters Kluwer)

Compare Atuss HX with other medications

• Cough

Where can I get more information?

• Your pharmacist can provide more information about guaifenesin and hydrocodone.

See also: Atuss HX side effects (in more detail)

In A Wink Daily Cleaner

Generic Name: sodium chloride (Ophthalmic route)

SOE-dee-um KLOR-ide

Commonly used brand name(s)

In the U.S.

• AK-NaCl


• Muro-128


• OcuFresh


• Sochlor

In Canada

• Cordema


• Eye Wash


• In A Wink Daily Cleaner


• In A Wink Neutralizing Rinse

Available Dosage Forms:

• Solution


• Ointment

Therapeutic Class: Osmotherapy Agent

Uses For In A Wink Daily Cleaner

Hypertonic sodium chloride solution for the eye is used to draw water out of a swollen cornea. The extra water in the cornea can cause your vision to be poor. You may also see halos or rings around point light sources. The cornea is the clear cover over the colored part of your eye.

This medicine is available only with your doctor's prescription.

Before Using In A Wink Daily Cleaner

In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

Allergies

Tell your doctor if you have ever had any unusual or allergic reaction to this medicine or any other medicines. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. For non-prescription products, read the label or package ingredients carefully.

Pediatric

Although there is no specific information comparing use of hypertonic sodium chloride in children with use in other age groups, this medicine is not expected to cause different side effects or problems in children than it does in adults.

Geriatric

Many medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. There is no specific information comparing use of hypertonic sodium chloride in the elderly with use in other age groups.

Interactions with Medicines

Although certain medicines should not be used together at all, in other cases two different medicines may be used together even if an interaction might occur. In these cases, your doctor may want to change the dose, or other precautions may be necessary. Tell your healthcare professional if you are taking any other prescription or nonprescription (over-the-counter [OTC]) medicine.

Interactions with Food/Tobacco/Alcohol

Certain medicines should not be used at or around the time of eating food or eating certain types of food since interactions may occur. Using alcohol or tobacco with certain medicines may also cause interactions to occur. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.

Proper Use of sodium chloride

This section provides information on the proper use of a number of products that contain sodium chloride. It may not be specific to In A Wink Daily Cleaner. Please read with care.

To use:

• The bottle is only partially full to provide proper drop control.


• First, wash your hands. Then tilt the head back and pull the lower eyelid away from the eye to form a pouch. Drop the medicine into the pouch and gently close the eyes. Do not blink. Keep the eyes closed for 1 or 2 minutes to allow the medicine to be absorbed.


• If you think you did not get the drop of medicine into your eye properly, use another drop.


• Immediately after using the eye drops, wash your hands to remove any medicine that may be on them.


• To keep the medicine as germ-free as possible, do not touch the applicator tip to any surface (including the eye). Also, keep the container tightly closed. Serious damage to the eye and possible loss of vision may result from using contaminated eye drops.

Dosing

The dose of this medicine will be different for different patients. Follow your doctor's orders or the directions on the label. The following information includes only the average doses of this medicine. If your dose is different, do not change it unless your doctor tells you to do so.

The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.

• For ophthalmic solution (eye drops) dosage form:
  
  • For swelling of the cornea:
    
    • Adults—Use 1 drop every three or four hours.
    
    
    • Children—Use and dose must be determined by your doctor.
    
    
  
  

Missed Dose

If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not double doses.

Storage

Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Keep out of the reach of children.

Do not keep outdated medicine or medicine no longer needed.

Ask your healthcare professional how you should dispose of any medicine you do not use.

Precautions While Using In A Wink Daily Cleaner

Use only under the advice and supervision of a doctor.

If you experience eye pain, changes in vision, continued redness or irritation of the eye, or if your symptoms continue for more than 3 days or become worse, check with your doctor.

Importance of not contaminating the product. Do not touch the tip of the container to the eye or any surface.

Do not use if the solution changes color or becomes cloudy.

Replace cap after each use. Store container upright.

In A Wink Daily Cleaner Side Effects

Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More Common

• temporary burning sensation of the eye


• temporary eye irritation

Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional.

Call your doctor for medical advice about side effects. You may report side effects to the FDA at 1-800-FDA-1088.

The information contained in the Thomson Reuters Micromedex products as delivered by Drugs.com is intended as an educational aid only. It is not intended as medical advice for individual conditions or treatment. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. Talk to your doctor, nurse or pharmacist before taking any prescription or over the counter drugs (including any herbal medicines or supplements) or following any treatment or regimen. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you.

The use of the Thomson Reuters Healthcare products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any of the information contained in the products. Additionally, THOMSON REUTERS HEALTHCARE MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Thomson Reuters Healthcare does not assume any responsibility or risk for your use of the Thomson Reuters Healthcare products.

More In A Wink Daily Cleaner resources

• In A Wink Daily Cleaner Support Group
• 0 Reviews · Be the first to review/rate this drug

Nexavar

Generic Name: sorafenib (sor a FEN ib)

Brand Names: NexAVAR

What is sorafenib?

Sorafenib is a cancer medication that interferes with the growth and spread of cancer cells in the body.

Sorafenib is used to treat a type of kidney cancer called advanced renal cell carcinoma. It is also used to treat liver cancer.

Sorafenib may also be used for purposes not listed in this medication guide.

What is the most important information I should know about sorafenib?

Do not use sorafenib if you are pregnant. It could harm the unborn baby. Use effective birth control while you are using this medication and for at least 2 weeks after your treatment ends, whether you are a man or a woman. Sorafenib use by either parent may cause birth defects. Do not breast-feed while using this medication. You should not use sorafenib if you are allergic to it, or if you have squamous cell lung cancer and you are being treated with carboplatin (Paraplatin) and paclitaxel (Onxol, Taxol, Abraxane).

Before you take sorafenib, tell your doctor if you have kidney or liver problems (other than cancer), a bleeding or blood clotting disorder, high blood pressure, heart disease, slow heartbeats, congestive heart failure, a personal or family history of Long QT syndrome, a history of stroke or heart attack, or any allergies.

If you need surgery or dental work, tell the surgeon or dentist ahead of time that you are taking sorafenib.

What should I discuss with my health care provider before taking sorafenib?

You should not use sorafenib if you are allergic to it, or if you have squamous cell lung cancer and you are being treated with carboplatin (Paraplatin) and paclitaxel (Onxol, Taxol, Abraxane).

To make sure you can safely take sorafenib, tell your doctor if you have any of these other conditions:

• 
  

  kidney or liver problems other than cancer;

  
  


• 
  

  lung cancer, especially if you are receiving gemcitabine (Gemzar) and cisplatin (Platinol);

  
  


• 
  

  a bleeding or blood clotting disorder such as hemophilia;

  
  


• 
  

  high blood pressure (hypertension), heart disease, slow heartbeats, congestive heart failure, chest pain;

  
  


• 
  

  a personal or family history of Long QT syndrome;

  
  


• 
  

  a history of stroke or heart attack; or

  
  


• 
  

  any allergies.

  
  

FDA pregnancy category D. Do not use sorafenib if you are pregnant. It could harm the unborn baby. Use effective birth control while you are using this medication and for at least 2 weeks after your treatment ends, whether you are a man or a woman. Sorafenib use by either parent may cause birth defects. It is not known whether sorafenib passes into breast milk or if it could harm a nursing baby. Do not breast-feed while using this medication.

How should I take sorafenib?

Take exactly as prescribed by your doctor. Do not take in larger or smaller amounts or for longer than recommended. Follow the directions on your prescription label.

Take sorafenib on an empty stomach, at least 1 hour before or 2 hours after eating. Do not crush, chew, or break a sorafenib tablet. Swallow it whole with water.

To be sure this medication is not causing harmful side effects, your blood pressure will need to be checked often. Visit your doctor regularly.

If you need surgery or dental work, tell the surgeon or dentist ahead of time that you are taking sorafenib. You may need to stop taking the medicine for a short time. Store at room temperature away from moisture and heat.

See also: Nexavar dosage (in more detail)

What happens if I miss a dose?

Take the missed dose as soon as you remember, but at least 2 hours since your last meal. Skip the missed dose if it is almost time for your next scheduled dose. Do not take extra medicine to make up the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222. Overdose symptoms may include severe diarrhea or severe skin rash.

What should I avoid while taking sorafenib?

Follow your doctor's instructions about any restrictions on food, beverages, or activity.

Sorafenib side effects

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Stop using sorafenib and call your doctor at once if you have a serious side effect such as:

• 
  

  rash, blisters, oozing, or severe pain in the palms of your hands or the soles of your feet;

  
  


• 
  

  mouth sores;

  
  


• 
  

  black or bloody stools, coughing up blood or vomit that looks like coffee grounds;

  
  


• 
  

  pale skin, feeling light-headed or short of breath, rapid heart rate, trouble concentrating;

  
  


• 
  

  easy bruising, unusual bleeding (nose, mouth, vagina, or rectum), purple or red pinpoint spots under your skin;

  
  


• 
  

  chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling;

  
  


• 
  

  dry cough, wheezing;

  
  


• 
  

  swelling, rapid weight gain, feeling short of breath (even with mild exertion);

  
  


• 
  

  sudden numbness or weakness, especially on one side of the body;

  
  


• 
  

  sudden weight loss, increased appetite, trouble sleeping, increased bowel movements, sweating, feeling hot, feeling nervous or anxious, swelling in your neck (goiter);

  
  


• 
  

  dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, confusion, uneven heartbeats, seizure); or

  
  


• 
  

  severe skin reaction -- fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.

  
  

Less serious side effects may include:

• 
  

  tired feeling;

  
  


• 
  

  nausea, vomiting, diarrhea, stomach pain, loss of appetite;

  
  


• 
  

  peeling or itchy skin, mild rash;

  
  


• 
  

  weight loss; or

  
  


• 
  

  thinning hair.

  
  

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

What other drugs will affect sorafenib?

Tell your doctor about all other cancer medicines you use, especially cyclophosphamide (Cytoxan, Neosar), docetaxel (Taxotere), doxorubicin (Adriamycin, Rubex), fluorouracil (Adrucil, Carac, Efudex, Fluoroplex), irinotecan (Camptosar), paclitaxel (Taxol) or tamoxifen (Soltamox).

The following drugs can interact with sorafenib. Tell your doctor if you are using any of these:

• 
  

  arsenic trioxide (Trisenox);

  
  


• 
  

  bosentan (Tracleer);

  
  


• 
  

  dexamethasone (Decadron, Hexadrol);

  
  


• 
  

  montelukast (Singulair) or zafirlukast (Accolate);

  
  


• 
  

  promethazine (Phenergan, Adgan, Anergan, Antinaus, Pentazine);

  
  


• 
  

  selegiline (Eldepryl, Emsam, Zelapar);

  
  


• 
  

  St. John's wort;

  
  


• 
  

  tacrolimus (Prograf);

  
  


• 
  

  voriconazole (Vfend);

  
  


• 
  

  an antibiotic such as clarithromycin (Biaxin), levofloxacin (Levaquin), neomycin (Mycifradin, Neo Fradin, Neo Tab), rifabutin (Mycobutin), rifampin (Rifadin, Rifater, Rifamate), and others;

  
  


• 
  

  an antidepressant;

  
  


• 
  

  anti-malaria medications such as chloroquine (Aralen) or mefloquine (Lariam);

  
  


• 
  

  a barbiturate such as pentobarbital (Nembutal) and others;

  
  


• 
  

  a blood thinner such as warfarin (Coumadin, Jantoven);

  
  


• 
  

  heart or blood pressure medications;

  
  


• 
  

  HIV medication;

  
  


• 
  

  medicine to prevent or treat nausea and vomiting such as dolasetron (Anzemet), droperidol (Inapsine), or ondansetron (Zofran);

  
  


• 
  

  medicines to treat narcolepsy;

  
  


• 
  

  medicines to treat psychiatric disorders, such as chlorpromazine (Thorazine), clozapine (FazaClo, Clozaril), haloperidol (Haldol), pimozide (Orap), and others;

  
  


• 
  

  migraine headache medicine such as sumatriptan (Imitrex, Treximet) and others;

  
  


• 
  

  narcotic medication such as methadone (Methadose, Diskets, Dolophine);

  
  


• 
  

  seizure medication such as carbamazepine (Carbatrol, Equetro, Tegretol), phenytoin (Dilantin), and others;

  
  


• 
  

  sulfa drugs (Bactrim, Gantanol, Gantrisin, Septra, SMX-TMP, and others); or

  
  


• 
  

  type 2 diabetes medications such as glimepiride (Amaryl), glipizide (Glucotrol), nateglinide (Starlix), pioglitazone (Actos, Actoplus Met), repaglinide (Prandin), rosiglitazone (Avandia, Avandamet), or tolbutamide (Orinase).

  
  

This list is not complete and other drugs may interact with sorafenib. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.

More Nexavar resources

• Nexavar Side Effects (in more detail)
• Nexavar Dosage
• Nexavar Use in Pregnancy & Breastfeeding
• Nexavar Drug Interactions
• Nexavar Support Group
• 3 Reviews for Nexavar - Add your own review/rating

• Nexavar Prescribing Information (FDA)


• Nexavar Monograph (AHFS DI)


• Nexavar Advanced Consumer (Micromedex) - Includes Dosage Information


• Nexavar Consumer Overview


• Nexavar MedFacts Consumer Leaflet (Wolters Kluwer)


• Sorafenib Professional Patient Advice (Wolters Kluwer)

Compare Nexavar with other medications

• Hepatic Tumor
• Hepatocellular Carcinoma
• Renal Cell Carcinoma
• Thyroid Cancer

Where can I get more information?

• Your pharmacist can provide more information about sorafenib.

See also: Nexavar side effects (in more detail)